Compositions of the seed oil of the<i>Borago officinalis</i>from Iran

Morteza, Elham; Akbari, Gholam Ali; Moaveni, Payam; Alahdadi, Iraj; Bihamta, M. R.; Hasanloo, Tahereh; Joorabloo, Ali

doi:10.1080/14786419.2014.971793

Cited by 9 publications

(6 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Borage leaves are an inexpensive crude material for the production of polyphenols, and disposal of these leaves needs a high cost, which can be limited by its utilization (Krishnaiah et al, 2011). Many unsaturated fatty acids, for example, palmitic, stearic, linoleic and α-linolenic acids are found in flowers of borage (Morteza et al, 2014 andRamandi et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Gastroprotective Effect of Borago Extracts against Indomethacin-Induced Gastric Ulcer in Rats

Gazwi

Mahmoud

2018

Journal of Food and Dairy Sciences

View full text Add to dashboard Cite

Gastric ulcer stays one of the perilous sicknesses in the world. In spite of the fact that there are numerous medications utilized for the treatment of gastric ulcer, the vast majority of these deliver a few adverse impacts. The aim of this investigation was to assess the antiulcer effects of Borago (Borago officinalis L) leaves extract (BL), flowers extract (BF) and the mixture of leaves and flowers extracts (Mix) against gastric ulcer induced by indomethacin in rats and compared with ranitidine as a reference drug. Gastric ulceration was stimulated by indomethacin at one dose (30 mg/kg b.w. Intraperitoneal (i.p)). BL and BF were administered orally at two doses of 100 and 200 mg/kg b.w, Mix was given orally at a dose of 200 mg/kg b.w. and ranitidine at a dose of 20 mg/kg b.w. for three weeks before the injection of indomethacin. The results appeared that indomethacin significantly decreased pH value, mucin content, catalase activity (CAT) and nitric oxide (NO), while, increased ulcer index, total acidity, free acidity and malondialdehyde (MDA) comparing with control group.While, pretreatment with Borago extracts provided a significant decrease in ulcer index, total acidity,free acidity, MDA, and associated with a significant rise in pH value, mucin content, CAT and NO compared to indomethacin group. The protection provided by the extracts of Borago is similar to ranitidine. Histological studies of stomach mucosa affirmed these outcomes. Borago has protective against indomethacin which caused gastric ulcer because of it contains antioxidant properties. The results of the present suggest that Borago can be utilized against gastric ulcer impacts as well as to decrease antagonist drugs adverse effects.

show abstract

Section: Introductionmentioning

confidence: 99%

Gastroprotective Effect of Borago Extracts against Indomethacin-Induced Gastric Ulcer in Rats

Gazwi

Mahmoud

2018

Journal of Food and Dairy Sciences

View full text Add to dashboard Cite

show abstract

“…Borago officinalis seed oil is used in pharmaceutical products, especially for its high content in α-linolenic acid, an essential and unusual fatty acid (10,43). It has been shown that palmitic, linoleic and stearic acids were dominant in the seed oil of borage (44). Wettasinghe and Shahidi investigated the antioxidant and reactive oxygen species (ROS) scavenging properties of borage meal extract (45,46).…”

Section: Discussionmentioning

confidence: 99%

Anxiolytic Effect of Borago officinalis (Boraginaceae) Extract in Male Rats

Komaki‬¹,

Rasouli²,

Shahidi³

2015

Avicenna J Neuro Psych Physio

View full text Add to dashboard Cite

Background: Medicinal plants with natural antioxidants have been shown to be beneficial in a variety of complications such as anxiety. The elevated plus-maze (EPM) is one of the most widely used models to assess anxiety in small rodents. Objectives: This study was designed to characterize the anxiolytic-like activity of Borago officinalis (Linnaeus, family Boraginaceae) or Borage flowers extract, using an EPM test. Materials and Methods: Male Wistar rats weighing 220-250 grams were used in the present study. Thirty minutes after an intraperitoneal (IP) injection of the Borage extract (50, 100, 200 mg/kg) or saline, each animal was placed in the EPM. Animal behaviors in the experimental sessions were recorded by a video camera located above the maze, interfaced with a monitor and a computer in an adjacent room. The time spent in the open arms, the percentage of entries into the open arms of the EPM and the numbers of entries into the closed arms were recorded for five minutes. Results: Statistical analysis indicated that acute IP injection of Borage extract before an EPM trial significantly increased the time spent in open arms and percentage of open arms entries. Whereas, the extract had no effect on the number of closed arm entries. Conclusions: Our results demonstrated that injection of Borage extract might have an anxiolytic profile in rats. However, the exact mechanism (s) related to the active compound (s) in Borage extract should be elucidated in future studies.

show abstract

“…Due to its potential market for gamma linolenic acid (GLA), it has been the subject of increasing agricultural interest and different fatty acids obtained from the seeds [130]. In addition to GLA, borage seeds contain stearic, erucic, linoleic, palmitic, oleic, α-linolenic, and erucic acids [131][132][133][134]. GLA is an omega-6 essential fatty acid that has been considered as having many positive therapeutic impacts, such as the treatment of diabetes, arthritis, heart disease, atopic eczema, cyclic mastalgia, and multiple sclerosis [135,136].…”

Section: Key Points Referencesmentioning

confidence: 99%

“…[123][124][125][126] The main reasons for membrane disruption are increased free fatty acid levels and free radical productivity by lipid per oxidation. [126][127][128][129][130] The seeds also contain palmitic, linoleic, stearic, α-linolenic, oleic, erucic, and erucic acids [130][131][132][133][134][135] Gamma-linolenic acid showed the potential to relieve the symptoms and signs of various chronic inflammatory diseases, such as atopic dermatitis and rheumatoid arthritis. [135][136][137][138][139][140] Gamma-linolenic acid can also be appropriate in respiratory, gastrointestinal, and cardiovascular disorders.…”

Section: Key Points Referencesmentioning

confidence: 99%

Five Important Seeds in Traditional Medicine, and Pharmacological Benefits

Shahrajabian

Sun

2023

Seeds

View full text Add to dashboard Cite

Knowledge about the pharmacological benefits of different seeds is an important factor for the cultivation and application of medicinal herbs and plants. The seeds of medicinal plants are stores of valuable and active secondary metabolites that have been commercially and economically beneficial and helpful for medicine and pharmacy. The major parameter of reproduction and the preservation of plants are seeds, which have a functional role in the distribution and establishment of plants in different regions. Five important seeds that have tremendous medicinal and pharmacological benefits are anise, basil, borage, cilantro, and chamomile. Anise seed is used as a spice, either whole or ground, and its essential oil and extract are also obtained from the seeds. Basil seeds have a long history of usage in Chinese and Ayurvedic medicine, and they are a good source of minerals, are high in fiber (including pectin), and are rich is flavonoids and other polyphenols. Borage seed oil is used for skin disorders, such as seborrheic dermatitis, atopic dermatitis, and neurodermatitis. Coriander is an annual herb that is part of the Apiaceae family, and the seeds are rich in iron, zinc, copper, and essential minerals, which can decrease bad cholesterol and improve good cholesterol in the body. Chamomile can be considered for the treatment of insomnia, hemorrhoids, anxiety, and diarrhea, and it may help with wound healing and skin irritation. Keyword searches for Anise, Seed, Basil, Borage, Cilantro, Chamomile, Seed biology, Traditional medicinal science, and seed anatomy were performed using Scopus, Web of Science, PubMed, and Google scholar. The aim of this article review is to survey the pharmacological and health benefits of the seeds of the five aforementioned important medicinal plants.

show abstract

Compositions of the seed oil of theBorago officinalisfrom Iran

Cited by 9 publications

References 6 publications

Gastroprotective Effect of Borago Extracts against Indomethacin-Induced Gastric Ulcer in Rats

Gastroprotective Effect of Borago Extracts against Indomethacin-Induced Gastric Ulcer in Rats

Anxiolytic Effect of Borago officinalis (Boraginaceae) Extract in Male Rats

Five Important Seeds in Traditional Medicine, and Pharmacological Benefits

Contact Info

Product

Resources

About