Comprehensive analysis of CPSF4-related alternative splice genes in hepatocellular carcinoma
Anwaier Yuemaierabola,
Jun Guo,
Lili Sun
et al.
Abstract:Background
An important stage in controlling gene expression is RNA alternative splicing (AS), and aberrant AS can trigger the development and spread of malignancies, including hepatocellular carcinoma (HCC). A crucial component of AS is cleavage and polyadenylation-specific factor 4 (CPSF4), a component of the CPSF complex, but it is unclear how CPSF4-related AS molecules describe immune cell infiltration in the total tumor microenvironment (TME).
Methods
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