This chapter examines the role of restorative approaches within cognitive rehabilitation. These approaches are discussed in the broader context of patient functioning, as articulated in the International Classification of Functioning, Disabilities, and Health (ICF) model. We discuss domains of cognitive functioning, including memory, attention, communication, visuospatial functioning, executive functioning, and emotional regulation/ control, and the impact of these domains individually and collectively on day-to-day activities. Conducting assessments for treatment planning is discussed with measurement of cognitive domains along with important historical, psychosocial, and environmental factors and assessment of key areas of functioning in order to accurately understand the nature of dysfunction in an individual' s day-to-day life and plan effective treatments. We discuss specific rehabilitation interventions and the importance of using restorative interventions together with compensatory interventions, such as are outlined in greater detail in Chapter 17 of this volume, to achieve the best treatment outcomes. Evolving areas of cognitive rehabilitation are also discussed, including the role of telerehabilitation, computer-based cognitive retraining, virtual reality, aerobic exercise, and pharmacologic interventions.
BACKGROUND Basic Neuroanatomy and Neuropathology of Brain Injury/IllnessAcquired brain injury (ABI) encompasses a broad range of both traumatic and nontraumatic illnesses that can produce neurological and neurocognitive deficits. The underlying etiology is variable, and multiple conditions can result in ABI, including cerebrovascular accident/stroke, brain tumors, traumatic brain injury (TBI), and autoimmune or infectious encephalopathies. Therefore, depending on pathology, the anatomical lesion may be focal or diffuse in nature. In the case of TBI, damage often occurs via diffuse injury impacting structural integrity and changes in underlying metabolic processes, which can cause white matter shearing, glial injury, and disrupted synaptic communication (Blennow et al., 2012;Hemphill et al., 2015). Although stroke typically produces more focal deficits, strokes occurring in watershed regions can cause deficits that affect multiple cognitive domains and motor functions (Kapasi et al., 2018). Brain tumors may impact both cortical gray matter and underlying white matter tracts, but they often produce more focal injuries (Taphoorn & Klein, 2004). However, unlike those with stroke and TBI, individuals with primary brain tumors and brain metastases can