Comprehensive Assessment of Changes in Left Atrial Volumes and Function after ST-Segment Elevation Acute Myocardial Infarction: Role of Two-Dimensional Speckle-Tracking Strain Imaging

Antoni, M. Louisa; Brinke, Ellen A. ten; Marsan, Nina Ajmone; Atary, Jael Z.; Holman, Eduard R.; Wall, Ernst E. van der; Schalij, Martin J.; Bax, Jeroen J.; Delgado, Victoria

doi:10.1016/j.echo.2011.06.017

Cited by 46 publications

(38 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…12 The use of TDE was somewhat limited by their angle dependency, noise interference, and disturbances caused by myocardial tethering. [45][46][47] Volume overload causes atrial remodeling (both structural and functional changes) including increase in interstitial fibrosis and decrease in atrial elasticity and decline in LA reservoir functions evaluated by STE-based global PALS. Atrial myocardial deformation has also been evaluated using this novel method in normal population and a number of cardiac pathologies.…”

Section: Discussionmentioning

confidence: 99%

Left Atrial Longitudinal Strain Parameters Predict Postoperative Persistent Atrial Fibrillation Following Mitral Valve Surgery: A Speckle Tracking Echocardiography Study

et al. 2013

View full text Add to dashboard Cite

Postoperative atrial fibrillation (POAF) is common after cardiac surgery and is associated with increased morbidity, mortality, and prolonged hospital stay. Speckle tracking echocardiography (STE) has been applied recently for evaluation of LA function. The purpose of this study was to examine whether left atrial longitudinal strain measured by STE is a predictor for the development of POAF following mitral valve surgery for severe mitral regurgitation. We studied 53 patients undergoing mitral valve surgery in sinus rhythm at the time of surgery. Echocardiography with evaluation of LA strain by STE was performed. Detection of POAF was based on documentation of AF episodes by continuous telemetry throughout hospitalization. Patients who did not develop POAF were taken as group 1 and those who had POAF constituted group 2. The echocardiographic and clinical predictors of POAF were investigated. POAF occurred in 28.3% of subjects. Mean age, LAVi and BNP were found higher in group 2 while peak atrial longitudinal strain (PALS) (13.9 ± 3.8% vs. 24.8 ± 7.3%; P < 0.001), peak atrial contraction strain (PACS) (7.6 ± 1.95% vs. 11.3 ± 3.5%; P < 0.001) were significantly lower. By multivariate logistic regression analysis, PALS and LAVi were independent predictor of POAF development. LA longitudinal strain was found to predict POAF in patients undergoing mitral valve surgery. It could be used to better identify patients at greater risk of developing POAF, and thus to guide in risk stratification and to take appropriate intensive prophylactic therapy.

show abstract

Section: Discussionmentioning

confidence: 99%

Left Atrial Longitudinal Strain Parameters Predict Postoperative Persistent Atrial Fibrillation Following Mitral Valve Surgery: A Speckle Tracking Echocardiography Study

et al. 2013

View full text Add to dashboard Cite

show abstract

“…The compensatory mechanism of stroke volume increase responded to volume change, but the difference became significant after a period of 1 month [4]. Left atrial remodeling, defined as increase in LA volume of 8 ml/m 2 has been shown to occur in about one fifth of patients after AMI leading to LA functional deterioration over a 12-month period [5].…”

Section: Discussionmentioning

confidence: 99%

“…Diastolic dysfunction in the setting of acute myocardial infarction (AMI) arises from profound regional asynchrony between ischemic and normal myocardium resulting in disturbed ventricular relaxation and elevated myocardial stiffness [3]. Several studies have demonstrated that LA undergoes significant remodelling following AMI due to increased left ventricular end-diastolic pressure (LVEDP) [4][5][6] and it has also been shown that LA volume is an important predictor of morbidity and mortality after AMI [7,8]. On the other hand, the relationship of duration of ischemia and LA volumes during acute phase of myocardial infarction has not been previously investigated.…”

Section: Introductionmentioning

confidence: 99%

Relationship of ischemic times and left atrial volume and function in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention

Ilić

Stanković

Vidaković

et al. 2015

Int J Cardiovasc Imaging

View full text Add to dashboard Cite

Little is known about the impact of duration of ischemia on left atrial (LA) volumes and function during acute phase of myocardial infarction. We investigated the relationship of ischemic times, echocardiographic indices of diastolic function and LA volumes in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). A total of 433 consecutive STEMI patients underwent echocardiographic examination within 48 h of primary PCI, including the measurement of LA volumes and the ratio of mitral peak velocity of early filling to early diastolic mitral annular velocity (E/e'). Time intervals from onset of chest pain to hospital admission and reperfusion were collected and magnitude of Troponin I release was used to assess infarct size. Patients with LA volume index (LAVI) ≥28 ml/m(2) had longer total ischemic time (410 ± 347 vs. 303 ± 314 min, p = 0.007) and higher E/e' ratio (15 ± 5 vs. 10 ± 3, p < 0.001) than those with LAVI <28 ml/m(2), while the indices of LA function were similar between the study groups (p > 0.05, for all). Significant correlation was found between E/e' and LA volumes at all stages of LA filling and contraction (r = 0.363-0.434; p < 0.001, for all) while total ischemic time along with E/e' and restrictive filling pattern remained independent predictor of LA enlargement. Increased LA volume is associated with longer ischemic times and may be a sensitive marker of increased left ventricular filling pressures in STEMI patients treated with primary PCI.

show abstract

“…The LA longitudinal strain and strain rate, which inversely related to LA wall fibrosis has been reported to be a feasible and reproducible method to assess LA myocardial function [2,16,21,22]. Recent researches have shown that LA strain is an independent predictor of the occurrence of LA remodelling and concomitant deterioration of LA function during followup [23–25]. In addition, LA strain has been related to LA structural remodelling and fibrosis of the atrial wall as assessed with magnetic resonance imaging [22].…”

Section: Discussionmentioning

confidence: 99%

Left Atrial Systolic and Diastolic Dysfunction in Patients with Chronic Constrictive Pericarditis: A Study Using Speckle Tracking and Conventional Echocardiography

Liu

Ren

et al. 2013

PLoS ONE

View full text Add to dashboard Cite

BackgroundLeft atrial (LA) function plays an important role in the maintenance of cardiac output, however, in patients with constrictive pericarditis (CP), whether pericardial restriction and adhesion can lead to LA dysfunction, and the characteristics of LA function remain unclear. The aim of the study is to compare the left atrial (LA) function of patients with CP to that of healthy study participants using speckle tracking echocardiography (STE) and conventional echocardiography.Methods and ResultsThirty patients with CP and 30 healthy volunteers (controls) were enrolled in the study. The underlying cause of CP was viral pericarditis in 24 (80%) patients and unknown in 6 (20%) patients. The LA maximum volume (Vmax), LA minimal volume (Vmin), and LA volume before atrial contraction (Vpre-a) were measured using biplane modified Simpson’s method. The LA expansion index (LA reservoir function) was determined as follows: ([LAVmax - LAVmin]/LAVmin) ×100. The passive emptying index (LA conduit function) was calculated as follows: ([LAVmax - LAVpre-a]/LAVmax) ×100, and the active emptying index (booster pump function) was calculated as follows: ([LAVpre-a - LAVmin]/LAVpre-a) ×100. All the patients underwent two-dimensional STE. The LA global systolic strain (S), systolic strain rate (SrS), early diastolic strain rate (SrE) and late diastolic strain rate (SrA) were measured. The LA expansion index, passive emptying index, the active emptying index and the LA global S, SrS, SrE, SrA were found to be significantly lower in patients with CP than in the control participants (P <0.001). LA function was correlated with the early diastolic velocity of the lateral mitral annulus (P <0.05).ConclusionsAlthough left ventricular systolic function was preserved in patients with CP, the LA reservoir, conduit, and booster functions were impaired. Pericardial restriction and impairment of the LA myocardium may play an important role in the reduction of LA function in patients with CP.

show abstract

Comprehensive Assessment of Changes in Left Atrial Volumes and Function after ST-Segment Elevation Acute Myocardial Infarction: Role of Two-Dimensional Speckle-Tracking Strain Imaging

Cited by 46 publications

References 21 publications

Left Atrial Longitudinal Strain Parameters Predict Postoperative Persistent Atrial Fibrillation Following Mitral Valve Surgery: A Speckle Tracking Echocardiography Study

Left Atrial Longitudinal Strain Parameters Predict Postoperative Persistent Atrial Fibrillation Following Mitral Valve Surgery: A Speckle Tracking Echocardiography Study

Relationship of ischemic times and left atrial volume and function in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention

Left Atrial Systolic and Diastolic Dysfunction in Patients with Chronic Constrictive Pericarditis: A Study Using Speckle Tracking and Conventional Echocardiography

Contact Info

Product

Resources

About