Comprehensive authenticity assessment of lavender oils using multielement/multicomponent isotope ratio mass spectrometry analysis and enantioselective multidimensional gas chromatography?mass spectrometry

Jung, Jochen; Sewenig, Sabine; Hener, Uwe; Mosandl, Armin

doi:10.1007/s00217-004-1049-4

Cited by 32 publications

(19 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Such analysis may be useful if oxygen resides in molecular positions where it does not exchange with water and therefore maintains its diagnostic isotopic fingerprint (e. g., in ether bridges as opposed to carboxyl groups). Indeed, compound-specific oxygen isotope analysis has been established for, and has delivered valuable information for, fragrance compounds [104,105]. In contrast, we are not aware of any applications of oxygen GC-IRMS for environmental contaminants.…”

Section: Chemical Modification Without Addition Of Protecting Groupsmentioning

confidence: 99%

Current challenges in compound-specific stable isotope analysis of environmental organic contaminants

et al. 2012

View full text Add to dashboard Cite

Compound-specific stable-isotope analysis (CSIA) has greatly facilitated assessment of sources and transformation processes of organic pollutants. Multielement isotope analysis is one of the most promising applications of CSIA because it even enables distinction of different transformation pathways. This review introduces the essential features of continuous-flow isotope-ratio mass spectrometry (IRMS) and highlights current challenges in environmental analysis as exemplified for the isotopes of nitrogen, hydrogen, chlorine, and oxygen. Strategies and recent advances to enable isotopic measurements of polar contaminants, for example pesticides or pharmaceuticals, are discussed with special emphasis on possible solutions for analysis of low concentrations of contaminants in environmental matrices. Finally, we discuss different levels of calibration and referencing and point out the urgent need for compound-specific isotope standards for gas chromatography-isotope-ratio mass spectrometry (GC-IRMS) of organic pollutants.

show abstract

Section: Chemical Modification Without Addition Of Protecting Groupsmentioning

confidence: 99%

Current challenges in compound-specific stable isotope analysis of environmental organic contaminants

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Still, published reports are appearing only slowly and focus primarily on its application for biochemical tracing [68] and natural products authentication [69][70][71][72] All GC-IRMS analyses of organic O rely on pyrolysis and reduction of organic molecules over carbon to quantitatively yield CO as the analyzed species. An additional concern for CO (relative to H 2 ) is the possibility of isotopic exchange between CO and Al 2 O 3 in the high-temperature pyrolysis reactor.…”

Section: Oxygen Isotopesmentioning

confidence: 99%

“…An additional concern for CO (relative to H 2 ) is the possibility of isotopic exchange between CO and Al 2 O 3 in the high-temperature pyrolysis reactor. For this reason, most systems utilize pyrolysis reactors constructed of alumina (typically 0.8 mm id) and lined with Pt or Ni tubes [68,70,71]. Pyrolysis/reduction reactors must be conditioned as for HD analyses by the periodic injection of organic compounds [70], and are typically operated at temperatures of 1200-13008C.…”

Section: Oxygen Isotopesmentioning

confidence: 99%

“…For this reason, most systems utilize pyrolysis reactors constructed of alumina (typically 0.8 mm id) and lined with Pt or Ni tubes [68,70,71]. Pyrolysis/reduction reactors must be conditioned as for HD analyses by the periodic injection of organic compounds [70], and are typically operated at temperatures of 1200-13008C. Ni wires are sometimes added as a catalyst and reductant, and 1% H 2 is commonly added to the helium carrier gas to maintain reducing conditions [69].…”

Section: Oxygen Isotopesmentioning

confidence: 99%

See 1 more Smart Citation

Isotope‐ratio detection for gas chromatography

Sessions¹

2006

J of Separation Science

244

270

View full text Add to dashboard Cite

Isotope-ratio detection for gas chromatographyInstrumentation and methods exist for highly precise analyses of the stable-isotopic composition of organic compounds separated by GC. The general approach combines a conventional GC, a chemical reaction interface, and a specialized isotoperatio mass spectrometer (IRMS). Most existing GC hardware and methods are amenable to isotope-ratio detection. The interface continuously and quantitatively converts all organic matter, including column bleed, to a common molecular form for isotopic measurement. C and N are analyzed as CO 2 and N 2 , respectively, derived from combustion of analytes. H and O are analyzed as H 2 and CO produced by pyrolysis/reduction. IRMS instruments are optimized to provide intense, highly stable ion beams, with extremely high precision realized via a system of differential measurements in which ion currents for all major isotopologs are simultaneously monitored. Calibration to an internationally recognized scale is achieved through comparison of closely spaced sample and standard peaks. Such systems are capable of measuring 13 C/ 12 C ratios with a precision approaching 0.1? (for values reported in the standard delta notation), four orders of magnitude better than that typically achieved by conventional "organic" mass spectrometers. Detection limits to achieve this level of precision are typically a1 nmol C (roughly 10 ng of a typical hydrocarbon) injected on-column. Achievable precision and detection limits are correspondingly higher for N, O, and H, in that order.

show abstract

“…In contrast, in spite of oxygen pyrolysis reactors for the online coupling of GC with IRMS having been available for about a decade,28 compound‐specific δ 18 O analysis of GC eluates (GC‐Py‐IRMS) has hardly been applied 29–32…”

mentioning

confidence: 99%

Compound‐specific δ¹⁸O analyses of neutral sugars in soils using gas chromatography–pyrolysis–isotope ratio mass spectrometry: problems, possible solutions and a first application

Zech

Glaser

2009

Rapid Comm Mass Spectrometry

View full text Add to dashboard Cite

Although gas chromatography-pyrolysis-isotope ratio mass spectrometry (GC-Py-IRMS) has allowed us to make online compound-specific delta18O measurements for about the last ten years, this technique has hardly been applied. We tested different pyrolysis reactor designs using standards (vanillin, ethylvanillin, a fatty acid methyl ester and alkanes) in order to optimize the GC-Py-IRMS delta18O measurements. The method was then applied to methylboronic acid (MBA) sugar derivatives (pentoses, 6-deoxyhexoses and hexoses). Plant- and microbial-derived monosaccharides were extracted hydrolytically from litter and topsoils before derivatization. The measured delta18O values of samples and co-analyzed reference material were first drift-corrected by use of regularly discharged pulses of CO reference gas. Secondly, they were corrected for the amount dependence of the delta18O values. Thirdly, the delta18O values were calibrated using the reference material (principle of 'Identical Treatment'), and, finally, a correction was applied by taking the hydrolytically introduced and water-exchangeable oxygen atoms into account. Our results suggest that the delta18O values of plant-derived monosaccharides in litter reflect the climatic conditions of the last year, whereas delta18O values of the respective topsoils reflect the averaged climate signal of the last decades or even centuries. This demonstrates the high potential of the method for palaeoclimate reconstructions.

show abstract

Comprehensive authenticity assessment of lavender oils using multielement/multicomponent isotope ratio mass spectrometry analysis and enantioselective multidimensional gas chromatography?mass spectrometry

Cited by 32 publications

References 8 publications

Current challenges in compound-specific stable isotope analysis of environmental organic contaminants

Current challenges in compound-specific stable isotope analysis of environmental organic contaminants

Isotope‐ratio detection for gas chromatography

Compound‐specific δ¹⁸O analyses of neutral sugars in soils using gas chromatography–pyrolysis–isotope ratio mass spectrometry: problems, possible solutions and a first application

Contact Info

Product

Resources

About

Comprehensive authenticity assessment of lavender oils using multielement/multicomponent isotope ratio mass spectrometry analysis and enantioselective multidimensional gas chromatography?mass spectrometry

Cited by 32 publications

References 8 publications

Current challenges in compound-specific stable isotope analysis of environmental organic contaminants

Current challenges in compound-specific stable isotope analysis of environmental organic contaminants

Isotope‐ratio detection for gas chromatography

Compound‐specific δ18O analyses of neutral sugars in soils using gas chromatography–pyrolysis–isotope ratio mass spectrometry: problems, possible solutions and a first application

Contact Info

Product

Resources

About

Compound‐specific δ¹⁸O analyses of neutral sugars in soils using gas chromatography–pyrolysis–isotope ratio mass spectrometry: problems, possible solutions and a first application