2022
DOI: 10.1080/21645698.2022.2079180
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Comprehensive COMPARE database reduces allergenic risk of novel food proteins

Abstract: The comprehensiveness of the allergen database used to bioinformatically compare a novel food protein with known allergens is critical to the ability to assess the allergenic risk of newly expressed proteins in genetically engineered crops. The strength of the relationship between a candidate GE protein’s amino acid sequence and that of known allergens is used to predict cross-reactive risk. The number of truly novel allergen sequences added annually to the COMPARE database reflects on the comprehensiveness of… Show more

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