Comprehensive comparison of global coagulation assays to differentiate lupus anticoagulant from acquired hemophilia A in patients with prolonged APTT

Chikasawa, Yushi; Amano, Kagehiro; Shinozawa, Keiko; Bingo, Masato; Miyashita, Ryui; Yamaguchi, Tomoko; Mitsuhashi, Ayano; Inaba, Hiroshi; Hagiwara, Takeshi; Kinai, Ei

doi:10.1007/s12185-023-03659-y

Int J Hematol

2023

DOI: 10.1007/s12185-023-03659-y

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Comprehensive comparison of global coagulation assays to differentiate lupus anticoagulant from acquired hemophilia A in patients with prolonged APTT

Yushi Chikasawa,

Kagehiro Amano,

Keiko Shinozawa

et al.

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2024

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Unexpected normal ROTEM results in protein C deficiency with IVC thrombosis

Kim,

Yoon

2024

BMJ Case Rep

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Protein C deficiency is a hereditary disorder that increases the risk of thrombotic events but has unclear effects on rotational thromboelastometry (ROTEM) analysis. A man in his 60s with a history of protein C deficiency and multiple thrombotic events underwent inferior vena cava (IVC) filter removal, iliocaval thrombectomy and infrarenal IVC placement for IVC-related complete iliocaval and common femoral vein thromboses. A ROTEM analysis showed normal coagulation in NATEM and EXTEM and only a slight shortening in A10 and A20 in INTEM, which was unexpected given his diagnosis of protein C deficiency. Normal results indicate that there is complexity and variability of coagulation to maintain a balanced state even in individuals with underlying coagulation disorders.

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Unexpected normal ROTEM results in protein C deficiency with IVC thrombosis

Kim,

Yoon

2024

BMJ Case Rep

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Comprehensive comparison of global coagulation assays to differentiate lupus anticoagulant from acquired hemophilia A in patients with prolonged APTT

Cited by 1 publication

References 51 publications

Unexpected normal ROTEM results in protein C deficiency with IVC thrombosis

Unexpected normal ROTEM results in protein C deficiency with IVC thrombosis

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