Comprehensive evaluation of a single-stage submaximal treadmill walking protocol in healthy, middle-aged women

Abstract

Cardiorespiratory fitness is an independent predictor of cardiovascular events in women; however, maximal oxygen consumption (VO(2max)) protocols are not always feasible. The Evaluation of Physical Activity Measures in Middle-Aged Women Study was a 6-week study designed to evaluate six physical activity (PA) measures in women, aged 45-65 years. We investigated the Ebbeling submaximal treadmill (EbbTM) protocol's ability to reflect an active lifestyle in 66 women [median (IQR) age, 51.0 (48.0, 56.5) years]. Participants were screened using ACSM and AHA guidelines and classified as moderate or low cardiovascular risk. VO(2max) was estimated using the EbbTM in all participants (TEST1). Moderate risk women repeated the EbbTM (TEST2) while low risk completed a maximal treadmill test. Intraclass correlation coefficients (ICC) and minimal detectable change (MDC(90)) score were calculated to examine reliability. Spearman rank order or Pearson product-moment correlation coefficients were used to determine the association between estimated VO(2max) and physical fitness and activity measures. Estimated VO(2max) from the EbbTM protocol had excellent reproducibility [ICC = 0.95 (95% CI: 0.89, 0.98) and MDC(90) was 1.62 mL kg(-1) min(-1). The EbbTM protocol was associated with measured VO(2max) (ρ = 0.48; p = 0.01) and was positively correlated with moderate- (ρ = 0.32; p = 0.02), vigorous- (ρ = 0.47; p = 0.0005) and moderate-to-vigorous-intensity PA (ρ = 0.36; p = 0.009), pedometer steps (ρ = 0.41; p = 0.002) and inversely correlated with waist circumference (ρ = -0.58; p < 0.0001), body fat (ρ = -0.55; p < 0.0001), and right leg endurance (ρ = -0.41; p = 0.003). The EbbTM protocol was shown to be reliable and associated with objective measures of fitness and PA in healthy, middle-aged women.

The impact of cardiorespiratory fitness on classical cardiovascular disease risk factors in rheumatoid arthritis: a cross-sectional and longitudinal study

“…The same poor CRF was observed in a cohort studied by our group [10]. Compared to healthy adults of similar age, RA patients have a significantly reduced CRF [8,[11][12][13]. Unfortunately, in rheumatology clinical practice, the measurement of CRF is generally nonexistent.…”

Waist circumference vs body mass index in association with cardiorespiratory fitness in healthy men and women: a cross sectional analysis of 403 subjects

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Enhanced insulin sensitivity in successful, long-term weight loss maintainers compared with matched controls with no weight loss history

“…38, 39 This protocol is a low-risk test for non-athletic adults. Treadmill walking speed is determined for each participant based on their age and fitness level.…”