Comprehensive geriatric assessment in female elderly patients with alzheimer disease and other types of dementia

Riccio, Daniela; Solinas, A; Astara, Giorgio; Mantovani, Giovanni

doi:10.1016/j.archger.2007.01.047

Cited by 28 publications

(17 citation statements)

References 34 publications

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“…CIRS-G severity index was 1.9, similar to previous reports (Doraiswamy et al, 2002). However, the median number of conditions (CIRS-G items) was 8 and the mean total CIRS-G score 13.8, higher than previously reported (Tekin et al, 2001;Doraiswamy et al, 2002;Riccio et al, 2007). Differences may be due to population characteristics (i.e., age, MMSE and dementia severity at baseline), type of clinical setting, or comorbidity evaluation methods.…”

Section: Discussionsupporting

confidence: 75%

“…Comorbidity seems to increase with dementia severity (van Dijk et al, 1996;Doraiswamy et al, 2002), and has been related to cognition in several cross-sectional studies (Doraiswamy et al, 2002;Lyketsos et al, 2005;Riccio et al, 2007). However, the association between comorbidity and cognitive decline over time is still unclear, as medical conditions are often considered separately.…”

Section: Introductionmentioning

confidence: 94%

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Comorbidity and the rate of cognitive decline in patients with Alzheimer dementia

Solomon

Dobranici

Kåreholt

et al. 2011

Int J Geriat Psychiatry

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Section: Discussionsupporting

confidence: 75%

Section: Introductionmentioning

confidence: 94%

Comorbidity and the rate of cognitive decline in patients with Alzheimer dementia

Solomon

Dobranici

Kåreholt

et al. 2011

Int J Geriat Psychiatry

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“…A potential limitation of this survey is the use of the MNA test as the gold standard, but in support of the validity of the study, it was carried out in a high number of volunteers. In any case, comprehensive geriatric assessment based on MNA has been applied in patients with psychiatric diseases (Riccio et al, 2007) and cognitive impairments (Arellano et al, 2004). 12 In conclusion, the high sensitivity and specificity of the subjective assessment (selfperception of nutritional and health status) to predict undernutrition, as determined by MNA test, suggested that it could be a good way to save many time in the daily clinical practice.…”

Section: Discussionmentioning

confidence: 99%

Impact of global and subjective mini nutritional assessment (MNA) questions on the evaluation of the nutritional status: The role of gender and age

Cuervo

Ansorena

Martínez‐González

et al. 2009

Archives of Gerontology and Geriatrics

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Undernutrition is a quite common condition in the elderly, often identified using the mini nutritional assessment (MNA) test. The aim of this research was to study the independent value of the global and the subjective MNA questions to predict the undernutrition according to the full MNA score, and to analyze the influence of gender and age on such items. A total of 22,007 Spanish people 65 years of age or older were evaluated using the MNA test. These data were obtained by trained community pharmacists by using receiver Operating Characteristic (ROC) curves. About 4.3% of the studied population were classified as undernourished according to the full MNA test. The subjective subscore (two questions) presented better predictive value than the global one (six questions). Indeed, 99.5% of subjects detected as well nourished using the MNA test were also correctly classified using the two subjective questions. In the present study, it was identified that the two subjective MNA questions can be an efficient tool for a quick screening to rule out non undernourished subjects.

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“…Thus, the combined effects of AD and lower limb fracture on ADL excluding cognitive functions and bathing were much larger than the sum of the sole effects of AD and fracture. The lack of an interaction for cognitive functions seems to be due to severe influences of AD on cognitive functions, for which complication with fracture did not bring any further deterioration [2,3].…”

Section: Discussionmentioning

confidence: 99%

“…The number of individuals with AD has been increasing considerably in recent years, accounting for more than 50 % of dementia cases [1]. AD causes cognitive impairment of elderly in need of care, consequently interfering with daily tasks and decreasing activities of daily living (ADL) in many ways [2]. It is known that patients with AD suffer from various kinds of complications [3].…”

Section: Introductionmentioning

confidence: 99%

Decreased activity of daily living produced by the combination of Alzheimer’s disease and lower limb fracture in elderly requiring nursing care

Inagawa

Hamagishi

Takaso

et al. 2012

Environ Health Prev Med

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Objectives Alzheimer's disease (AD) impairs cognitive functions, subsequently decreasing activity of daily living (ADL), and is frequently accompanied by lower limb fracture including hip fracture in the elderly. However, there have been few studies on what kinds of physical functions are affected or what degrees of dysfunction are produced by this combination. This study aims to clarify the relationship between decreased ADL and the combination of AD and lower limb fracture. Methods We examined present illness and ADL in 4340 elderly aged 82.8 ± 9.36 years [average ± standard deviation (SD)] requiring nursing care and compared ADL between elderly with and without AD or lower limb fracture treated with surgery or conservatively using analysis of covariance (ANCOVA), with age and sex as covariants. Results We recognized that activities of cognitive function (p \ 0.001), eating (dysphagia) (p \ 0.001), eating (feeding) (p \ 0.001), and toilet use (p \ 0.001) in the elderly with AD were significantly lower than in those without the disease, even after adjusting for sex and age. Activities of bed mobility (p \ 0.05), transfer and locomotion (p \ 0.001), and bathing (p \ 0.05) in the elderly with a fracture treated with surgery were significantly lower, which differed from the results of AD. Significant interactions of AD and fracture treated with surgery on the ADL scores for bed mobility (p \ 0.001), dysphagia (p \ 0.01), feeding (p \ 0.001), and toilet use (p \ 0.05) show that the combination had a much more profound influence on the ADL scores than AD or fracture alone. We obtained almost the same results for fractures treated conservatively as for fractures treated with surgery. Conclusions These results demonstrated that the combined effects of AD and lower limb fracture were significantly greater than expected additive effects of AD and fracture, suggesting that the combination of AD and lower limb fracture has synergistic effects on almost all types of ADL except cognitive functions.

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Comprehensive geriatric assessment in female elderly patients with alzheimer disease and other types of dementia

Cited by 28 publications

References 34 publications

Comorbidity and the rate of cognitive decline in patients with Alzheimer dementia

Comorbidity and the rate of cognitive decline in patients with Alzheimer dementia

Impact of global and subjective mini nutritional assessment (MNA) questions on the evaluation of the nutritional status: The role of gender and age

Decreased activity of daily living produced by the combination of Alzheimer’s disease and lower limb fracture in elderly requiring nursing care

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