Comprehensive Review of Phytochemical Profiles and Health-Promoting Effects of Different Portions of Wampee (Clausena lansium)

Abstract

Clausena lansium, commonly known as wampee, is a subtropical fruit from the Rutaceae family characterized by its high nutrient content and numerous bioactive substances. This low-fat fruit is abundant in fiber, vitamins, minerals, and essential amino acids. Wampee has been found to contain several bioactive compounds, including essential oils, phenolic compounds, and alkaloids. These bioactive constituents provide numerous health-enhancing properties, such as antioxidant, neuroprotective, anticarcinogenic, anti-inflammatory, hepatoprotective, antidiabetic, and antimicrobial effects. The relationship between these compounds and their impacts on health has been explored in various studies. While the disease-prevention efficacy of C. lansium has been established, additional research is necessary to elucidate the precise mechanisms and metabolic pathways involved. This paper presents a comprehensive review of wampee, focusing on its bioactive compounds, the beneficial effects derived from its consumption, and the evidence supporting the development of wampee-based functional foods in future studies.

Phytochemical Profiling Studies of Alkaloids and Coumarins from the Australian Plant Geijera parviflora Lindl. (Rutaceae) and Their Anthelmintic and Antimicrobial Assessment

“…The antinociceptive, anti-inflammatory and antioxidant properties of constituent alkaloids and coumarins which are in keeping with the traditional use of Fagaropsis hildebrandtii in Kenya, were corroborated through various assays [27]. Alkaloids and coumarins from Clausena lansium which is used traditionally in China and Southeast Asia to treat bronchitis, asthma, hepatitis, and gastrointestinal disorders have displayed significant anti-inflammatory properties [28,29]. Evodia lepta, a herb used in traditional Chinese medicine (TCM) to treat chronic inflammatory conditions such as arthritis as well as infections such as influenza, was found to contain a racemic mixture of an alkaloid with significant anti-neuroinflammatory activity, and the use of other compounds from this plant have been suggested for the treatment of dementia [30,31].…”

The effect and mechanism of volatile oil emulsion from leaves of Clausena lansium (Lour.) Skeels on Staphylococcus aureus in vitro

“…Clausena lansium (Lor.) Skeels (wampee) are plants of the Rutaceae family that are widely cultivated in the Lingnan region of China and have a long medicinal history (Huang et al, 2023). The seedless wampee is a rare fruit unique to Lingnan County in Guangdong Province.…”

Trends in carbazole synthesis – an update (2013–2023)

“…Indeed, the significance of carbazoles for medicinal applications is well-known. As such, higher plants of the genus Murraya , Glycosmis and Clausena , have long-standing application in folk treatments of fever, 6 liver disease, 7 bronchitis, 8 malaria, 9 snakebites 10 and more. Nonetheless, it was not until 1965 that Chakraborty described the isolation and antibiotic properties of murrayanine from Murraya koenigii – the first report of a naturally occurring carbazole alkaloid.…”