2023
DOI: 10.1002/jssc.202300304
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Comprehensive two‐dimensional gas chromatography— A discussion on recent innovations

Nino B. L. Milani,
Eric van Gilst,
Bob W. J. Pirok
et al.

Abstract: Although comprehensive 2‐D GC is an established and often applied analytical method, the field is still highly dynamic thanks to a remarkable number of innovations. In this review, we discuss a number of recent developments in comprehensive 2‐D GC technology. A variety of modulation methods are still being actively investigated and many exciting improvements are discussed in this review. We also review interesting developments in detection methods, retention modeling, and data analysis.

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Cited by 12 publications
(1 citation statement)
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“…Comprehensive two-dimensional gas chromatography (GC × GC, Figure A) uses two columns of different stationary phases so that vapor analytes are subjected to two independent separations to achieve a peak capacity higher than the corresponding one-dimensional GC. A modulator is placed between the first-dimensional ( 1 D) and second-dimensional ( 2 D) columns and periodically sends a portion of the 1 D effluent to the 2 D column. Usually, a pneumatic modulator or thermal modulator is used to achieve so-called snapshot modulation or accumulative modulation. , …”
Section: Introductionmentioning
confidence: 99%
“…Comprehensive two-dimensional gas chromatography (GC × GC, Figure A) uses two columns of different stationary phases so that vapor analytes are subjected to two independent separations to achieve a peak capacity higher than the corresponding one-dimensional GC. A modulator is placed between the first-dimensional ( 1 D) and second-dimensional ( 2 D) columns and periodically sends a portion of the 1 D effluent to the 2 D column. Usually, a pneumatic modulator or thermal modulator is used to achieve so-called snapshot modulation or accumulative modulation. , …”
Section: Introductionmentioning
confidence: 99%