Compressibility of porous magnesium foam: dependency on porosity and pore size

Wen, Cuié; Yamaguchi, Yasuo; Shimojima, Koji; Chino, Yasumasa; Hosokawa, Hiroyuki; Mabuchi, Mamoru

doi:10.1016/s0167-577x(03)00500-7

Cited by 255 publications

(135 citation statements)

References 17 publications

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“…This behavior indicates the bulk deformation of scaffolds under the compression load, however, porous magnesium specimens produced by metal foaming method [82] and powder sintering method [48] show local collapse of pores with shortened elastic deformation. Following the linear elastic deformation ending at the yield strength, normally magnesium samples exhibit a long plateau of constant stress [82].…”

Section: Accepted M Manuscriptmentioning

confidence: 99%

“…Changing the pore size, pore shape, porosity, and pore distribution can affect the mechanical properties [48,83,84]. Increasing porosity results in the decrease of compression strength, yield strength, and Young's modulus [48,83,84].…”

Section: Accepted M Manuscriptmentioning

confidence: 99%

“…Increasing porosity results in the decrease of compression strength, yield strength, and Young's modulus [48,83,84]. The mechanical properties of porous magnesium prepared by the green compacts method using carbamide particles as the space holder and under 100 MP uniaxial pressure were studied to demonstrate the dependence of mechanical properties on pore size and porosity [48]. Scaffolds with pore size of 70-400 µm and porosity of 35-55%…”

Section: Accepted M Manuscriptmentioning

confidence: 99%

“…On the other hand, in the untreated osteocartilage defect with the highest accessibility to bone marrow cavity, no reproduction of subchondral bone in the central part was observed [118]. Magnesium scaffolds with optimal porosity should provide appropriate mechanical support [47,48], osteoinductive properties, excellent biocompatibility [121], biodegradability and bioresorbability [122]. Thus, such scaffolds can be designed to be suitable candidates for subchondral bone plate replacement.…”

Section: Cartilagementioning

confidence: 99%

“…The presence of porosity adversely affects the corrosion resistance by enhancing the surface area exposed to the corrosive media [48]. In order to control the degradability of Mg scaffolds produced by powder metallurgy method, a multilayer polymeric matrix composed of polycaprolactone (PCL) and gelatin (Gel) reinforced with bioactive glass (BaG) particles has been coated on the surface of Mg scaffolds by freeze drying process [49].…”

mentioning

confidence: 99%

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Porous magnesium-based scaffolds for tissue engineering

Yazdimamaghani

Razavi

Vashaee

et al. 2017

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Section: Accepted M Manuscriptmentioning

confidence: 99%

Section: Accepted M Manuscriptmentioning

confidence: 99%

Section: Accepted M Manuscriptmentioning

confidence: 99%

Section: Cartilagementioning

confidence: 99%

mentioning

confidence: 99%

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Porous magnesium-based scaffolds for tissue engineering

Yazdimamaghani

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Progress and Challenge for Magnesium Alloys as Biomaterials

et al. 2008

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Magnesium alloys are very biocompatiable and show promise for use in orthopaedic implant. Significant progress of research on bioabsorbable magnesium stents and orthopaedic bones has been achieved in recent years. The issues on degradation, hydrogen evolution, and corrosion fatigue and erosion corrosion of magnesium alloys and various influencing factors in simulated body fluid (SBF) are discussed. The research progress on magnesium and its alloys as biomaterials and miscellaneous approaches to enhancement in corrosion resistance is reviewed. Finally the challenges and strategy for their application as orthopaedic biomaterials are also proposed.

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A Novel Manufacturing Route for Fabrication of Topologically‐Ordered Porous Magnesium Scaffolds

et al. 2011

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The use of porous metal foams as biomaterial scaffolds has been widely adopted; however, many of these porous structures are manufactured with pore architectures that are inherently random. This makes structural optimization for a specific purpose challenging. Scaffolds containing ordered pore architectures can be fabricated to meet design criteria, such as porosity, stiffness, and volume fraction. Mg and its alloys offer potential as a new class of degradable metallic orthopedic biomaterials. In comparison with current metallic orthopedic implant materials, Mg offers advantages such as, closer‐to‐bone stiffness and biodegradability, thereby eliminating the need for a second surgery to remove hardware. Currently there are few methods described in literature to manufacture ordered porous Mg. The aim of this study was to determine the resolution of a novel indirect solid free‐form fabrication (SFF) process for producing topologically ordered Mg (TOPM) structures. The multi‐step method involved the printing of an SFF mould, NaCl infiltration, and liquid Mg casting techniques. Using a range of characterization methods, we demonstrated that the selected structures were manufactured with a high level of accuracy. Differences in dimensions from CAD models to Mg scaffolds ranged from 2.5% to a maximum of 8.33%. Similarly, there was a maximum of 6.1% reduction in porosity in Mg scaffolds compared with initial design. Meanwhile, with surface roughness of 10.17 ± 1.75 µm, there was an average of 70% increase in surface area. This study demonstrates a simple, reliable, and safe route to manufacture TOPM scaffolds for potential application in medical device design.

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Compressibility of porous magnesium foam: dependency on porosity and pore size

Cited by 255 publications

References 17 publications

Porous magnesium-based scaffolds for tissue engineering

Porous magnesium-based scaffolds for tissue engineering

Progress and Challenge for Magnesium Alloys as Biomaterials

A Novel Manufacturing Route for Fabrication of Topologically‐Ordered Porous Magnesium Scaffolds

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