Compression device to reduce motion artifacts at contrast-enhanced MR imaging in the breast.

Schorn, C.; Fischer, Uwe; Döler, W.; Funke, M.; Grabbe, E.

doi:10.1148/radiology.206.1.9423684

Cited by 11 publications

(6 citation statements)

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“…40 For a clinical trial of four patients with DbPET/CT, in which no immobilization of the breast was used, one set of PET images was not interpretable due to misregistration between the PET and CT. 15 Segmenting the reconstructed PET volume instead of the CT implicitly reduces this problem; however, mild compression of the breast is another potential solution and we plan on implementing an immobilization scheme comparable to that used in breast MRI. 41 Furthermore, it is expected that the larger transaxial FOV (20 versus 12 cm) and the significantly higher SNR of images from the CT compared with the PET will allow for more accurate segmentation of the breast volume.…”

Section: Discussionmentioning

confidence: 99%

Quantification with a dedicated breast PET/CT scanner

2012

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Purpose: Dedicated breast PET/CT is expected to have utility in local staging, surgical planning, monitoring of therapy response, and detection of residual disease for breast cancer. Quantitative metrics will be integral to several such applications. The authors present a validation of fully 3D data correction schemes for a custom built dedicated breast PET/CT (DbPET/CT) scanner via 18 F-FDG phantom scans. Methods: A component-based normalization was implemented, live-time was estimated with a multicomponent model, and a variance reduced randoms estimate was computed from delayed coincidences. Attenuation factors were calculated by using a CT based segmentation scheme while scatter was computed using a Monte Carlo (MC) simulation method. As no performance standard currently exists for breast PET systems, custom performance tests were created based on prior patient imaging results. Count-rate linearity for live-time and randoms corrections was measured with a decay experiment for a solid polyethylene cylinder phantom with an offset line source. A MC simulation was used to validate attenuation correction, a multicompartment phantom with asymmetric activity distribution provided an assessment of scatter correction, and image uniformity after geometric and detector normalization was measured from a high count scan of a uniform cylinder phantom. Raw data were reconstructed with filtered back projection (FBP) after Fourier rebinning. To quantify performance absolute activity concentrations, contrast recovery coefficients and image uniformity were calculated through region of interest analysis. Results: The most significant source of error was attributed to mispositioning of events due to pileup, presenting in count-related axial and transaxial nonuniformities that were not corrected for with the normalization method used here. Within the range of singles counts observed during clinical trials residual error after applying all corrections was comparable to that of a commercial whole body PET/CT system. Conclusions: The results suggest that DbPET/CT is capable of producing quantitative images under the operating conditions expected during patient imaging. V C 2012 American Association of Physicists in Medicine. [http://dx

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Section: Discussionmentioning

confidence: 99%

Quantification with a dedicated breast PET/CT scanner

2012

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“…These include non‐image‐based techniques such as immobilization, (3) , (4) although it has been our experience that immobilization of cancer patients can be self‐defeating due to increased patient anxiety. One class of image‐based techniques to reduce motion artifacts involves retrospective image registration and is incorporated into a number of public‐domain postprocessing software packages, including SPM, AIR, and AFNI.…”

Section: Introductionmentioning

confidence: 99%

Real‐time motion detection of functional MRI data

Steger

Jackson

2004

J Applied Clin Med Phys

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The objective of this work was to implement a motion‐detection algorithm on a commercial real‐time functional magnetic resonance imaging (fMRI) processing package for neurosurgical planning applications. A real‐time motion detection module was implemented on a commercial real‐time processing package. Simulated functional data sets with introduced translational, in‐plane rotational, and through‐plane rotational motion were created. The coefficient of variation (COV) of the center of intensity was used as a motion quantification metric. Coefficients of variation were calculated before and after image registration to determine the effectiveness of the motion correction; the limits of correctability were also determined. The motion‐detection module allowed for real‐time quantification of the motion in an fMRI experiment. Along with knowledge of the limits of correctability, this enables determination of whether an experiment needs to be reacquired while the patient is in the scanner. This study establishes the feasibility of using real‐time motion detection for presurgical planning fMRI and establishes the limits of correctable motion.PACS number: 87.61.‐c

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“…Artifacts may result in loss of conspicuity of the lesion and shadowing and blurring of tumor margins. Despite techniques such as respiratory gating, shallow breathing, and simple ventral stuffing of the bottom of the coil, motion artifact in the CE dynamic subtracted images still exists (12).…”

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confidence: 99%

Negative pressure fixation device to reduce motion artifacts on contrast‐enhanced MRI of the breast: A clinical feasibility study

Balakrishnan

Kacher

Gombos

et al. 2009

Magnetic Resonance Imaging

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Purpose:To investigate the effect of a negative pressure fixation device on misregistration artifacts in contrast-enhanced (CE) MR subtraction images. Materials and Methods:Nine patients, two of which had been previously diagnosed with breast cancer, were examined with T2-weighted (T2-w) turbo spin-echo (TSE) and three-dimensional (3D) spoiled gradient-recalled echo (SPGR) CE dynamic MRI. Baselines images were subtracted from the dynamic images. A device consisting of two stiff plastic domes was placed on the breasts of each patient. Negative pressure of 27 to 37 mmHg within the domes was maintained. The patient was positioned prone in the coil without the device and imaged as a baseline. Subsequently, the patient was placed into the negative pressure domes and reimaged. One of the nine patients was also imaged supine to establish feasibility for this positioning. Results:With the use of the negative pressure fixation device, a reduction in misregistration artifact has been demonstrated in prone imaging. Patients reported improved comfort with the device and feasibility has been shown for supine imaging. Conclusion:The device was shown to be MRI-compatible and successfully applied in this pilot study, opening other avenues of exploration. Supine positioning for breast imaging makes possible better access for biopsy and intervention. Further modifications to the device are in order for this purpose and to eliminate motion due to breathing in the prone position.

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Compression device to reduce motion artifacts at contrast-enhanced MR imaging in the breast.

Cited by 11 publications

References 0 publications

Quantification with a dedicated breast PET/CT scanner

Quantification with a dedicated breast PET/CT scanner

Real‐time motion detection of functional MRI data

Negative pressure fixation device to reduce motion artifacts on contrast‐enhanced MRI of the breast: A clinical feasibility study

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