Computational Analysis of Nucleotide-Dependent Mechanical Properties of Microtubule Protofilaments

Abstract

dimers of dimers), and these low-level associations will be demonstrated. These results provide additional insight into the regulation of heterodimers of tubulin from different biological sources, suggesting that monomer exchange may contribute to the sorting of aand b-tubulin monomers that associate following tubulin folding, and that dimer -dimer association may form species important for further polymerization.