Computational Chemistry in Early-Stage Drug Discovery

Brooijmans, Natasja

doi:10.1158/aacr.edb-08-8252

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…LHC searches have benefitted immensely from developments in jet substructure techniques over the past many years and have enabled investigations of many hitherto challenging signals. Starting from the earlier ideas in jet substructure [20][21][22][23] we now have a large toolkit of methods suited to a diverse array of theoretical and experimental challenges. As mentioned, the lack of any unambiguous indications of new physics at collider and non-collider experiments is perplexing though.…”

Section: Introductionmentioning

confidence: 99%

Looking for minimal inverse seesaw scenarios at the LHC with jet substructure techniques

Bhardwaj

Das²,

Konar

et al. 2020

J. Phys. G: Nucl. Part. Phys.

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Simple extensions of the Standard Model (SM) with additional Right Handed Neutrinos (RHNs) can elegantly explain the existence of small neutrino masses and their flavor mixings. Collider searches for sterile neutrinos are being actively pursued currently. Heavy RHNs may dominantly decay into W ± ∓ after being produced at the LHC. In this paper, we consider collider signatures of heavy pseudo-Dirac neutrinos in the context of inverse seesaw scenario, with a sizable mixing with the SM neutrinos under two different flavor structures, viz., Flavor Diagonal and Flavor Non-Diagonal textures. For the latter scenario we use a general parametrization for the model parameters by introducing an arbitrary orthogonal matrix and nonzero Dirac and Majorana phases. We then perform a parameter scan to identify allowed parameter regions which satisfy all experimental constraints. As an alternative channel to the traditional trilepton signature, we propose the oppositesign di-lepton signature in the final state, in association with a fat jet from the hadronic decay of the boosted W ± . We specifically consider a fat jet topology and explore the required enhancements from exploiting the characteristics of the jet substructure techniques. We perform a comprehensive collider analysis to demonstrate the effectiveness of this channel in both of the scenarios, significantly enhancing the bounds on the RHN mass and mixing angles at the 13 TeV LHC.

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Section: Introductionmentioning

confidence: 99%

Looking for minimal inverse seesaw scenarios at the LHC with jet substructure techniques

Bhardwaj

Das²,

Konar

et al. 2020

J. Phys. G: Nucl. Part. Phys.

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“…This is mainly due to the fact that chiral enhancement as well as RG effects that enhance the dangerous Q LR operators are much smaller in the B d,s systems than in the K system. • Finally, the model allows naturally for S ψφ as high as 0.4 as hinted at by the most recent CDF and DØ data [38,39,40] and by an order of magnitude larger than the SM expectation, S ψφ ≃ 0.04. The strong correlation between S ψφ and A s SL shown in Figure 4 then would imply a significant departure of the latter observable from its tiny SM value.…”

Section: Discussionmentioning

confidence: 81%

K and B meson mixing in warped extra dimensions with custodial protection

Duling

2009

J. Phys.: Conf. Ser.

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After a brief theoretical introduction of the warped extra-dimensional model with custodial protection the results of [1] are presented. In this work we analyze the impact of Kaluza-Klein (KK) gauge boson modes on ∆F = 2 observables, for the first time considering the full operator basis and including NLO renormalization group running. It is pointed out that the dominant contribution in the B-system does not come from the KK gluon, but that contributions from KK excitations of the weak gauge bosons are competitive. In a numerical analysis we assess the amount of fine-tuning necessary for obtaining realistic values for quark masses and mixings and at the same time realistic values for ǫK , the measure for CP violation in K meson mixing. We are able to show that a mass of the lightest KK gauge boson of 2-3 TeV, and hence in the reach of the LHC, is still possible for moderate fine-tuning. These results enable us to make predictions for not yet measured ∆F = 2 observables, such as S ψφ and A SL s , which can differ significantly from their SM values.

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Computational Chemistry in Early-Stage Drug Discovery

Cited by 2 publications

References 9 publications

Looking for minimal inverse seesaw scenarios at the LHC with jet substructure techniques

Looking for minimal inverse seesaw scenarios at the LHC with jet substructure techniques

K and B meson mixing in warped extra dimensions with custodial protection

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