Utilization of Archimedes screw pumps as water lifting pumps has become widespread in past decade due to frequent occurrences of floods in Malaysia. The problem of insufficient drainage in various urban areas exacerbates the impact of heavy rainfall, prompting efforts to mitigate this issue with minimal maintenance cost and low impact to the environment. Thus, this study is aiming to study the design parameters of screw pump to obtain the optimal efficiency of the Archimedes screw pump specifically for flood mitigation in Malaysia. The main design parameters affecting pump’s efficiency are rotor profile, pitch length, length of the pump, rotational speed, inclination angle, and material selection. However, only three design parameters were considered in the study, that are the angle of inclination, the number of blades, and the angular velocity of the rotating pump. These three design parameters are selected as many previous findings focusing on varying angle of inclination with number of blades with constant rotational speed. Thus, this study will find the highest efficiency when these three design parameters are integrated with variation of rotational speeds at 25, 30 and 40 RPM. Basically, screw pump is designed using SOLIDWORKS and simulations with specific boundary conditions are conducted using the ANSYS-CFX software, which utilizes computational fluid dynamics (CFD) techniques. These boundary conditions are based on previous study by Rosly et al in 2016. The inlet flow rate of 0.002 m3/s and diameter of the screw pump are constant while the other three main parameters are varying within the acceptable ranges which are reported from prior studies. The outcomes found that the highest torque is generated by a single rotating blade at 5.65 Nm which rotates at 30 RPM at 30° angle of inclination. Meanwhile, the highest efficiency of 24.04% is obtained with a single rotating blade at 40 RPM with 20° angle of inclination. Based on the findings, it is concluded that these three main design parameters of screw pump may not be sufficient to obtain the optimal efficiency for the specific boundary conditions used in the simulation study. Thus, several combinations of design parameters should be considered in the future to increase the screw pump’s efficiency.