Computational fluid dynamics and experimental investigations on liquid–liquid mass transfer in T-type microchannels with different mixing channel barrier shapes

Hosseini, Fardin; Rahimi, Masoud

doi:10.1080/01496395.2019.1706569

Cited by 7 publications

(8 citation statements)

References 33 publications

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“…The maximum pressure drop was observed when temperature difference between the continuous and dispersed fluid was −10 • C. Chen and Chen [74] during their analysis of fractal micromixers with obstacles found that the ∆P depended on the height of the obstacle and the rate of increase in ∆P was non-linear after Re = 10. Hosseini and Rahimi [76] compared their four different micromixer designs and found that the Cylindrical Barrier Micromixer (CBM) exhibited the highest pressure drop, 1.8 to 2.4 times higher than the plain microchannel, due to the formation of more vortices. The lowest pressure drop was shown by their Semi Conical Barrier Micromixer design (SCoM) due to the absence of fluid rotation.…”

Section: Effect Of Geometric and Operating Parameters On Pressure Dro...mentioning

confidence: 99%

A Review of Pressure Drop and Mixing Characteristics in Passive Mixers Involving Miscible Liquids

Ganguli,

Bhatt,

Yagodnitsyna

et al. 2024

Micromachines

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The present review focuses on the recent studies carried out in passive micromixers for understanding the hydrodynamics and transport phenomena of miscible liquid–liquid (LL) systems in terms of pressure drop and mixing indices. First, the passive micromixers have been categorized based on the type of complexity in shape, size, and configuration. It is observed that the use of different aspect ratios of the microchannel width, presence of obstructions, flow and operating conditions, and fluid properties majorly affect the mixing characteristics and pressure drop in passive micromixers. A regime map for the micromixer selection based on optimization of mixing index (MI) and pressure drop has been identified based on the literature data for the Reynolds number (Re) range (1 ≤ Re ≤ 100). The map comprehensively summarizes the favorable, moderately favorable, or non-operable regimes of a micromixer. Further, regions for special applications of complex micromixer shapes and micromixers operating at low Re have been identified. Similarly, the operable limits for a micromixer based on pressure drop for Re range 0.1 < Re < 100,000 have been identified. A comparison of measured pressure drop with fundamentally derived analytical expressions show that Category 3 and 4 micromixers mostly have higher pressure drops, except for a few efficient ones. An MI regime map comprising diffusion, chaotic advection, and mixed advection-dominated zones has also been devised. An empirical correlation for pressure drop as a function of Reynolds number has been developed and a corresponding friction factor has been obtained. Predictions on heat and mass transfer based on analogies in micromixers have also been proposed.

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Section: Effect Of Geometric and Operating Parameters On Pressure Dro...mentioning

confidence: 99%

A Review of Pressure Drop and Mixing Characteristics in Passive Mixers Involving Miscible Liquids

Ganguli,

Bhatt,

Yagodnitsyna

et al. 2024

Micromachines

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“…Several examples in the literature have utilized computational fluid dynamics (CFD) or finite element modeling (FEM) simulations to analyze various aspects of their microfluidics devices. Commonly, simulations are used to evaluate the effects of microchannel geometry changes on flow conditions [ 67 , 88 , 98 , 138 , 139 , 140 , 141 ]. They can also be used to analyze the effect of channel geometry on reaction processes [ 47 , 142 ].…”

Section: Democratizing 3dp Droplet Microfluidicsmentioning

confidence: 99%

Can 3D Printing Bring Droplet Microfluidics to Every Lab?—A Systematic Review

et al. 2021

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In recent years, additive manufacturing has steadily gained attention in both research and industry. Applications range from prototyping to small-scale production, with 3D printing offering reduced logistics overheads, better design flexibility and ease of use compared with traditional fabrication methods. In addition, printer and material costs have also decreased rapidly. These advantages make 3D printing attractive for application in microfluidic chip fabrication. However, 3D printing microfluidics is still a new area. Is the technology mature enough to print complex microchannel geometries, such as droplet microfluidics? Can 3D-printed droplet microfluidic chips be used in biological or chemical applications? Is 3D printing mature enough to be used in every research lab? These are the questions we will seek answers to in our systematic review. We will analyze (1) the key performance metrics of 3D-printed droplet microfluidics and (2) existing biological or chemical application areas. In addition, we evaluate (3) the potential of large-scale application of 3D printing microfluidics. Finally, (4) we discuss how 3D printing and digital design automation could trivialize microfluidic chip fabrication in the long term. Based on our analysis, we can conclude that today, 3D printers could already be used in every research lab. Printing droplet microfluidics is also a possibility, albeit with some challenges discussed in this review.

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“…Those authors used 3D printing technology to fabricate the micromixers with different shapes of barriers like cylindrical, semi-cylindrical, conical, and semi-conical. The efficiency of the cylindrical barrier was around 23.7-83.7% [17].…”

Section: Introductionmentioning

confidence: 96%

“…Also, for counting, detecting, and sorting of microparticles, the sheath flow focusing and sheathless focusing theory was applied in microfluidic devices [12]. Jian et al designed a microfluidic device that can successfully detect 6 out of 8 non-small cell lung cancer (NSCLC), and Hongmei et al explored with micro-ellipse filters for particles and there are small tunnels which gives less chance to escape [13][14][15][16][17][18][19][20][21][22][23][24][25].…”

Section: Introductionmentioning

confidence: 99%

Design and Numerical Simulation of Biomimetic Structures to Capture Particles in a Microchannel

Yang

Joseph

Unnam

et al. 2022

Fluids

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The study of separating different sizes of particles through a microchannel has been an interest in recent years and the primary attention of this study is to isolate the particles to the specific outlets. The present work highly focuses on the design and numerical analysis of a microchip and the microparticles capture using special structures like corrugated dragonfly wing structure and cilia walls. The special biomimetic structured corrugated wing is taken from the cross-sectional area of the dragonfly wing and cilia structure is obtained from the epithelium terminal bronchioles to the larynx from the human body. Parametric studies were conducted on different sizes of microchip scaled and tested up in the range between 2–6 mm and the thickness was assigned as 80 µm in both dragonfly wing structure and cilia walls. The microflow channel is a low Reynolds number regime and with the help of the special structures, the flow inside the microchannel is pinched and a sinusoidal waveform pattern is observed. The pinched flow with sinusoidal waveform carries the particles downstream and induces the particles trapped in desired outlets. Fluid particle interaction (FPI) with a time-dependent solver in COMSOL Multiphysics was used to carry out the numerical study. Two particle sizes of 5 µm and 20 µm were applied, the inlet velocity of 0.52 m/s with an inflow angle of 50° was used throughout the study and it suggested that: the microchannel length of 3 mm with corrugated dragonfly wing structure had the maximum particle capture rate of 20 µm at the mainstream outlet. 80% capture rate for the microchannel length of 3 mm with corrugated dragonfly wing structure and 98% capture rate for the microchannel length of 2 mm with cilia wall structure were observed. Numerical simulation results showed that the cilia walled microchip is superior to the corrugated wing structure as the mainstream outlet can conduct most of the 20 µm particles. At the same time, the secondary outlet can laterally capture most of the 5 µm particles. This biomimetic microchip design is expected to be implemented using the PDMS MEMS process in the future.

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Computational fluid dynamics and experimental investigations on liquid–liquid mass transfer in T-type microchannels with different mixing channel barrier shapes

Cited by 7 publications

References 33 publications

A Review of Pressure Drop and Mixing Characteristics in Passive Mixers Involving Miscible Liquids

A Review of Pressure Drop and Mixing Characteristics in Passive Mixers Involving Miscible Liquids

Can 3D Printing Bring Droplet Microfluidics to Every Lab?—A Systematic Review

Design and Numerical Simulation of Biomimetic Structures to Capture Particles in a Microchannel

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