Computational Modeling for Intelligent Surface Plasmon Resonance Sensor Design and Experimental Schemes for Real‐Time Plasmonic Biosensing: A Review

Abstract

The spectacular physical phenomenon of surface plasmon resonance (SPR) is the essence of present‐day plasmonic sensors. Meanwhile, the unique properties of the interaction between light and matter have been carved out into the development of modern‐day diagnostic biosensors. Plasmons, in simple terms, are oscillating free electrons in metallic nano‐structures triggered by an incoming electromagnetic (EM) wave. With the advantages of real‐time and label‐free bio‐sensing, plasmonic sensors are being utilized in multiple diverse areas of food technology, the bio‐medical diagnostic sector, and even the chemical industry. Although this review will be brief, readers can gain a comprehensive picture of the essential elements by taking a broader look into the exploration of SPR sensor design via simulated studies and representative experimental plasmonic schemes developed for bio‐sensing. In short, the various SPR sensing schemes that researchers have explored to realize enhanced SPR sensitivity are reviewed and summarized. Different experimental plasmonic sensors are also examined in which new SPR excitation schemes have been adopted. These "unconventional" designs, specifically those involving hybrid localized surface plasmon resonance (LSPR)‐SPR excitation, may inspire those in the plasmonic field.

The Characterization and Study of Antibacterial, Free Radical Scavenging, and Anticancer Potential of Livistona chinensis-Mediated Silver Nanoparticles

“…The frequency of the incident light matches the natural frequency of the electron oscillations, satisfying the resonance condition. This resonance leads to a strong absorption and scattering of light by the nanoparticles [44]. In this study, no absorbance peak was visible in the plant extract.…”

Optical Biosensor Based on Porous Silicon and Tamm Plasmon Polariton for Detection of CagA Antigen of <em>Helicobacter Pylori</em>

“…Among these available biosensing techniques, optical biosensors have the advantages of high sensitivity, good specificity, easy operation, fast response, portability, and compatibility with optoelectronic integration. To illustrate the advantages, optical biosensors based on waveguides [15], ring resonators [16], resonant microcavities [17], photonic crystals [18], optic fibers [19], Surface Plasmon Resonance (SPR) [20], Localized Surface Plasmon Resonance (LSPR) [21], and Surface Enhanced Raman Spectroscopy (SERS) [22], have been proposed as effective detectors of various kinds of bio species, such as and biomarkers, proteins, DNAs, virus, bacterium, and cells. On the other hand, from the material perspective of biosensing technology, porous silicon (PSi) is a versatile nanoscale material for biosensing applications.…”

Chiral nanomaterials in tissue engineering

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