Computational Modelling of Multi-folded Balloon Delivery Systems for Coronary Artery Stenting: Insights into Patient-Specific Stent Malapposition

Ragkousis, Georgios E.; Curzen, Nick; Bressloff, Neil W.

doi:10.1007/s10439-014-1237-8

Cited by 17 publications

(11 citation statements)

References 42 publications

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“…To achieve this, the FE procedure was implemented under quasi‐static analysis conditions and the following components were included: balloon, guide wire, the catheter shaft, atherosclerotic coronary artery, and stent. Similar implementations of this simulation can be found in numerous studies …”

Section: Methodsmentioning

confidence: 99%

“…A value of 2.65 mm for D b 0 was found as the better fit. The element type used to mesh the balloon was a 4‐node quadrilateral membrane element with reduced integration …”

Section: Methodsmentioning

confidence: 99%

“…To approve a new stent design for clinical use, finite element (FE) analysis of stent models are requested by regulatory agencies such as the Food and Drug Administration (FDA) . In this regard, the method has proven noteworthy not only in providing a better understanding of the overall physical behavior of the stent itself and the delivery system but also of the interactions occurring between these medical devices and the arterial wall during PCI . Of the numerous computational models published in the literature focusing on different stent issues, almost all share the same final goal: improvement of the device's clinical performance.…”

Section: Introductionmentioning

confidence: 99%

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Surrogate‐based visualization and sensitivity analysis of coronary stent performance: A study on the influence of geometric design

Ribeiro

Folgado

Rodrigues

2018

Numer Methods Biomed Eng

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The main goal of this numerical study is to assess the impact of geometric design perturbations on the performance of a representative coronary stent platform. In this context, first, a design parameterization model was defined for the stent under study. After, a set of metrics characterizing stent performance, namely, vessel injury, radial recoil, bending resistance, longitudinal resistance, radial strength, the risk of fracture, prolapse index, and dogboning were evaluated within the context of a finite element analysis. Afterwards, accurate surrogate models were developed, using the efficient global optimization algorithm, as predictive tools in the execution of tasks that normally require a high number of model evaluations, such as global sensitivity analysis and visualization. In the end, the dependence of the output response surfaces on the geometric parameters was mechanically interpreted, which allowed us to understand the complex interplay that exists between the considered design variables and the defined performance metrics.

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Section: Methodsmentioning

confidence: 99%

“…A value of 2.65 mm for D b 0 was found as the better fit. The element type used to mesh the balloon was a 4‐node quadrilateral membrane element with reduced integration …”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Surrogate‐based visualization and sensitivity analysis of coronary stent performance: A study on the influence of geometric design

Ribeiro

Folgado

Rodrigues

2018

Numer Methods Biomed Eng

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“…The proximal diameter-referenced expansion strategy led to the highest vessel stress. High arterial stress induced by stent expansion has been predicted by previous studies [11][12][13][14], and arterial wall stress has been associated with the formation of neointimal hyperplasia and in-stent restenosis [3]. On the other hand, the proximal diameter-referenced expansion strategy may be the best choice for tapered vessels where stent apposition is concerned.…”

Section: Discussionmentioning

confidence: 87%

“…Finite element method (FEM) has been widely applied to investigate the different mechanical properties of stents due to its low cost and high efficiency [9][10][11][12][13][14]. Several studies have used FEM to investigate stent expansion modeling methods.…”

Section: Introductionmentioning

confidence: 99%

Effect of different expansion strategies on coronary stent deployment in a tapered artery

Shen¹,

Ji²,

Xie³

et al. 2017

THC

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Abstract. BACKGROUND: Vascular stenting has been widely used to treat vessel stenosis. However, long-term successes of the procedure are often compromised by late stent thrombosis (ST) and in-stent restenosis (ISR), especially in tapered arteries. OBJECTIVE: The aim of this study was to choose a reasonable expansion strategy for tapered arteries. METHODS: A balloonexpandable coronary stent deployment in a tapered vessel was numerically studied fol-lowing three strategies: (i) selecting the proximal diameter of the tapered vessel as the reference diameter to expand the stent, (ii) selecting the middle diameter of the tapered vessel as the reference diameter to expand the stent, and (iii) selecting the distal diameter of the tapered vessel as the reference diameter to expand the stent. RESULTS: Computational results showed that the first expansion strategy resulted in the maximum vessel stress and the best stent apposition, while the third strategy resulted in the minimal vessel stress and the worst stent appo-sition. Meanwhile, the second expansion strategy achieved a trade-off between the first and third strategies, leading to acceptable vessel stress and stent apposition. CONCLUSIONS: The second expansion strategy is the most reasonable choice for tapered vessels, and it should be considered when implanting a stent.

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Investigation of Drug Eluting Stents Performance Through in silico Modeling

Loukas

Pleouras

Karanasiou

et al. 2020

8th European Medical and Biological Engineering Conference

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Computational Modelling of Multi-folded Balloon Delivery Systems for Coronary Artery Stenting: Insights into Patient-Specific Stent Malapposition

Abstract: 12Despite the clinical effectiveness of coronary artery stenting, percutaneous coro-

Cited by 17 publications

References 42 publications

Surrogate‐based visualization and sensitivity analysis of coronary stent performance: A study on the influence of geometric design

Surrogate‐based visualization and sensitivity analysis of coronary stent performance: A study on the influence of geometric design

Effect of different expansion strategies on coronary stent deployment in a tapered artery

Investigation of Drug Eluting Stents Performance Through in silico Modeling

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