Computational models for the determination of depth-dependent mechanical properties of skin with a soft, flexible measurement device

Yuan, Julin; Dağdeviren, Canan; Shi, Yan; Ma, Yinji; Feng, Xue; Rogers, John A.

doi:10.1098/rspa.2016.0225

Cited by 20 publications

(12 citation statements)

References 33 publications

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“…Alterations of the skin micro-and macro-topography have important consequences in applications where stable and long-term adhesion of external devices to the skin surface are sought, such as in medical adhesives [139,140] and deformable electronics [141] for epidermal sensing and monitoring applications [142][143][144]. These latter applications are particularly relevant as evidenced by the growing widespread use of telemedicine for the elderly [145] which increasingly relies on ambulatory in vivo health monitoring systems.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Biotribology of the ageing skin—Why we should care

et al. 2019

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Ageing of populations has emerged as one of the most pressing societal, economic and healthcare challenges currently facing most nations across the globe. The ageing process itself results in degradation of physiological functions and biophysical properties of organs and tissues, and more particularly those of the skin. Moreover, in both developed and emerging economies, population ageing parallels concerning increases in lifestyleassociated conditions such as Type 2 diabetes, obesity and skin cancers. When considered together, these demographic trends call for even greater urgency to find clinical and engineering solutions for the numerous age-related deficits in skin function. From a tribological perspective, detrimental alterations of skin bioph ysical properties with age have fundamental consequences on how one interacts with the body's inner and outer environments. This stems from the fact that, besides being the largest organ of the human body, and also nearly covering its entirety, the skin is a multifunctional interface which mediates these interactions. The aim of this paper is to present a focused review to discuss some of the consequences of skin ageing from the viewpoint of biotribology, and their implications on health, well -being and human activities. Current and future research questions/challenges associated with biotribology of the ageing ski n are outlined. They provide the background and motivation for identifying future lines of research that could be taken up by the biotribology and biophysics communities.

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Section: Accepted Manuscriptmentioning

confidence: 99%

Biotribology of the ageing skin—Why we should care

et al. 2019

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“…The skin, which is a complex and the largest organ by surface area, acts as the first line of defense and has diverse functions, such as prevention from trauma, temperature regulation, reduces effects of UV rays, and acts as a sensory organ 22,23 . It is a multilayered heterogeneous material with the topmost layer epidermis which contains the stratum corneum and viable epidermis, the dermis which contains several type collagens with diverse orientations, and the hypodermis which generally contains subcutaneous fat covering the muscles 24–27 . For epidermis, the thickness values range from 0.07 to 0.12 mm, whereas for dermis, it is between 1 and 4 mm depending upon the location considered over the body 28–30 .…”

Section: Methodsmentioning

confidence: 99%

Biomechanical modeling of novel high expansion auxetic skin grafts

Gupta¹,

Gupta²,

Chanda

2022

Numer Methods Biomed Eng

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Over 20 million burn injuries are reported every year, with severe cases requiring skin grafting. Traditionally, split thickness skin grafts are prepared by excising a small portion of healthy skin and its incision patterning using a suitable meshing device, which allows the graft to be expanded beyond its capacity. To date, the maximum expansion achieved through skin grafting has been reported to be less than three times, which is not sufficient for covering large burn sites with limited donor site skin. In this work, we have attempted to study skin graft expansion potential with novel auxetic patterns, which are known to exhibit negative Poisson's effect. Two‐layer skin graft models were developed using eight different auxetic incision patterns, and subjected to uniaxial and biaxial tensile strains. The Poisson's ratio, meshing ratio, and induced stresses were characterized for all graft models. The numerical results indicated expansion potentials greater than that of traditional skin grafts across all loads. Extremely high expansions (i.e., >30 times) were estimated for the I‐Shaped Re‐entrant and Rotating Triangles shaped auxetic models without rupture. Such pioneering findings are anticipated to initiate ground‐breaking advances towards skin graft research and improved outcomes in burn surgeries.

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“…Because it comprises the intra-body pressure, the low-pressure span, which corresponds to both intraocular and intracranial pressures, is crucial. Blood pressure, heart rate, radial artery wave, phonation vibration, and skin modulus are all examples of body pressure in the medium pressure span [129]. The weight of a human or atmospheric pressure at high altitudes is included in the high-pressure span [130].…”

Section: Development In Wearable P Sensing Apparatusesmentioning

confidence: 99%

Revolution in Flexible Wearable Electronics for Temperature and Pressure Monitoring—A Review

2022

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In the last few decades, technology innovation has had a huge influence on our lives and well-being. Various factors of observing our physiological characteristics are taken into account. Wearable sensing tools are one of the most imperative sectors that are now trending and are expected to grow significantly in the coming days. Externally utilized tools connected to any human to assess physiological characteristics of interest are known as wearable sensors. Wearable sensors range in size from tiny to large tools that are physically affixed to the user and operate on wired or wireless terms. With increasing technological capabilities and a greater grasp of current research procedures, the usage of wearable sensors has a brighter future. In this review paper, the recent developments of two important types of wearable electronics apparatuses have been discussed for temperature and pressure sensing (Psensing) applications. Temperature sensing (Tsensing) is one of the most important physiological factors for determining human body temperature, with a focus on patients with long-term chronic conditions, normally healthy, unconscious, and injured patients receiving surgical treatment, as well as the health of medical personnel. Flexile Psensing devices are classified into three categories established on their transduction mechanisms: piezoresistive, capacitive, and piezoelectric. Many efforts have been made to enhance the characteristics of the flexible Psensing devices established on these mechanisms.

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Computational models for the determination of depth-dependent mechanical properties of skin with a soft, flexible measurement device

Cited by 20 publications

References 33 publications

Biotribology of the ageing skin—Why we should care

Biotribology of the ageing skin—Why we should care

Biomechanical modeling of novel high expansion auxetic skin grafts

Revolution in Flexible Wearable Electronics for Temperature and Pressure Monitoring—A Review

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