Computational nanoscience and technology

Rajput, Amarjitsing; Sevalkar, Ganesh; Pardeshi, Krutika

doi:10.1016/j.onano.2023.100147

Cited by 11 publications

(6 citation statements)

References 114 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Biosensors are yet another dimension of application in which nanotechnology has enabled the development of highly sensitive biosensors that can detect even low levels of biomolecules in bodily fluids such as blood and urine, facilitating early detection and disease management [ 20 , 21 ]. Similar applications come in the form of microfluidic devices that incorporate nanomaterials and can be used to isolate and analyze specific cells, proteins, and genetic material, providing rapid and accurate diagnosis of diseases [ 19 , 22 ]. Another use may involve nanopore sequencing, which is a novel technology that uses nanopores to detect the sequence of DNA or RNA molecules, allowing for rapid and accurate diagnosis of genetic disorders such as cancer and genetic diseases [ 23 ].…”

Section: Results and Discussion—applications Of Nanotechnology In The...mentioning

confidence: 99%

“…[ 19 , 25 , 26 ]. In in vivo diagnostics, the nanomedicine approach is being used to develop devices capable of working, responding, and modifying within the human body with the sole purpose of early diagnosis of any irregularities in the human body that could lead to toxicity or tumor development events [ 22 , 27 ]. A few types of nanoparticles that are currently in use for diagnostic purposes include paramagnetic nanoparticles, nanocrystals, quantum dots, nanoshells, and nanosomes [ 28 , 29 ].…”

Section: Results and Discussion—applications Of Nanotechnology In The...mentioning

confidence: 99%

“…The latest advances in research indicate that modern programing optimization and in silico approaches are being adopted to design DNA nanostructures with precise size, structure, surface chemistry, and functioning properties against specific diseases [ 22 , 52 ]. The effort is also to create personalized targeted drug therapies using nanotechnology-based DNA medicine [ 51 ].…”

Section: Results and Discussion—applications Of Nanotechnology In The...mentioning

confidence: 99%

See 2 more Smart Citations

Emerging Applications of Nanotechnology in Healthcare and Medicine

Malik,

Muhammad,

Waheed

2023

Molecules

124

View full text Add to dashboard Cite

Knowing the beneficial aspects of nanomedicine, scientists are trying to harness the applications of nanotechnology in diagnosis, treatment, and prevention of diseases. There are also potential uses in designing medical tools and processes for the new generation of medical scientists. The main objective for conducting this research review is to gather the widespread aspects of nanomedicine under one heading and to highlight standard research practices in the medical field. Comprehensive research has been conducted to incorporate the latest data related to nanotechnology in medicine and therapeutics derived from acknowledged scientific platforms. Nanotechnology is used to conduct sensitive medical procedures. Nanotechnology is showing successful and beneficial uses in the fields of diagnostics, disease treatment, regenerative medicine, gene therapy, dentistry, oncology, aesthetics industry, drug delivery, and therapeutics. A thorough association of and cooperation between physicians, clinicians, researchers, and technologies will bring forward a future where there is a more calculated, outlined, and technically programed field of nanomedicine. Advances are being made to overcome challenges associated with the application of nanotechnology in the medical field due to the pathophysiological basis of diseases. This review highlights the multipronged aspects of nanomedicine and how nanotechnology is proving beneficial for the health industry. There is a need to minimize the health, environmental, and ethical concerns linked to nanotechnology.

show abstract

Section: Results and Discussion—applications Of Nanotechnology In The...mentioning

confidence: 99%

Section: Results and Discussion—applications Of Nanotechnology In The...mentioning

confidence: 99%

Section: Results and Discussion—applications Of Nanotechnology In The...mentioning

confidence: 99%

See 1 more Smart Citation

Emerging Applications of Nanotechnology in Healthcare and Medicine

Malik,

Muhammad,

Waheed

2023

Molecules

124

View full text Add to dashboard Cite

show abstract

“…Nanoscale systems have several advantages because their small size gives them better dispersion, plus their large surface area makes them more attractive to targets (Rajput, Sevalkar, Pardeshi, & Pingale, 2023). Utilizing quantum dots (QDs) in Bt formulations can help overcome these limitations and allow for commercial production.…”

Section: Introductionmentioning

confidence: 99%

Enhancing the UV Radiation Protection of Bacillus thuringiensis Formulation using Sulfur Quantum Dots: A Biotechnological Approach

Jalali,

Maghsoudi

2024

Preprint

View full text Add to dashboard Cite

Low stability against ultraviolet (UV) radiation is one of the drawbacks of biological pesticides such as Bacillus thuringiensis (Bt). The persistence of Bt crystals against insect pests is thus deactivated. Bt plays a key role in the control of microbial pests. In this study, Bt spores and crystals were protected from UV radiation by sulfur quantum dots (SQDs). These were synthesized by treating sublimated sulfur powders with an alkali using polyethylene glycol 400 (PEG-400). Their effect on the formulation of Bt was investigated to improve its resistance to UV radiation. Excellent aqueous dispersibility and superior photostability were observed for the synthesized SQDs. Properly dispersed SQDs with mean size distributions of 3.27 nm and 6.07 nm were obtained for 120 and 72 h, respectively. The findings indicate that SQDs perform very well in encapsulated formulations prepared by the Pickering emulsion method compared to non-encapsulated formulations. Spore viability and mortality of second-instar Ephestia kuehniella larvae under UV-A radiation were studied. The unique properties of SQDs are believed to reduce the degradation of Bt against UV radiation. Our results showed that these SQDs can be used to improve the stability and resistance of Bt in SQD-stabilized microcapsule formulations.

show abstract

“…In order to create intelligent nanoscale vehicles, a brand-new multidisciplinary study area called nanobiotechnology combines nanoscience with the biological environment. These vectors may be loaded with more medication and released under the right circumstances [1][2][3][4][5]. With the incorporation of biological substitutes like living cells, biomolecules, biocompatible and biodegradable synthetic materials, or natural materials that can restore, maintain, and improve the function of tissues or organs, tissue engineering aims to restore, repair, and replace damaged and diseased tissues [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Organic-Inorganic Composites Based on Multi-walled Carbon Nanotubes ‎ Containing Lysine/Histidine

Haroun,

Ayoob,

Masoud

2023

Egypt. J. Chem.

View full text Add to dashboard Cite

Carbon nanotubes (CNTs) have been employed alone or in composites with other substances to generate highly useful materials in a variety of industries. They are especially promising as scaffolds for bone tissue regeneration. To the best of our knowledge, no studies have been published on the usage of lysine (Lys) or histidine (His) for functionalizing oxidised Multiwalled carbon nanotubes (ox-MWCNTs) using the sol-gel process. The goal of this research is to create innovative hybrid composites for biomedical applications based on ox-MWCNTs incorporating tetra ethyl orthosilicate (TEOS) and various amino acids (Lys or His). Fourier transform infrared spectroscopy (FTIR), dynamic light scattering technique (DLS), X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning and transmission electron microscopes (SEM and TEM) were used to characterise the physicochemical properties.. In vitro bone bioactivity was tested after 7 days of soaking in simulated body fluid (SBF) at 37 °C, as well as cytotoxicity against mice bone marrow stromal cells using the MTT assay. The results showed that both functionalized MWCNTs had particle sizes of 1332 and 1329 nm and are colloidal stable. After soaking the composites in SBF, SEM pictures revealed aggregated ca-apatite layers on the surface. After soaking for 7 days, the calcium element and the liberated free amino acids concentrations in the residual SBF were approximately (2.1 and 0.9) and (2.6 and 2.0) mg/L in the case of both amino acids, respectively. It can be concluded that both covalent attached amino acids play enhancement role for the ca-apatite formation and lowering the toxicity in the hybrid composites relative to the ox-MWCNTs especially in the case of His.

show abstract

Computational nanoscience and technology

Cited by 11 publications

References 114 publications

Emerging Applications of Nanotechnology in Healthcare and Medicine

Emerging Applications of Nanotechnology in Healthcare and Medicine

Enhancing the UV Radiation Protection of Bacillus thuringiensis Formulation using Sulfur Quantum Dots: A Biotechnological Approach

Organic-Inorganic Composites Based on Multi-walled Carbon Nanotubes ‎ Containing Lysine/Histidine

Contact Info

Product

Resources

About