HighlightsA case of internal abdominal herniation through a defect in transverse mesocolon with congenital abnormality of hands and feets.Reduction along with derotation of gut with closure of the rent and fixation of the caecum to lateral peritoneum done.Due to the risk of strangulation of the hernial contents, even small internal hernias are dangerous.Herniation through transverse mesocolon is very rare and preoperative diagnosis of mesenteric defect is difficult.Surgical decision-making is on the basis of clinical findings of intestinal strangulation or ischemia.