Computed Tomographic Findings in COVID-19

Joob, Beuy; Wiwanitkit, Viroj

doi:10.3348/kjr.2020.0164

Cited by 3 publications

(3 citation statements)

References 8 publications

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“…The former represents the absorption outcome of a type of lesion with a “pleura parallel sign”, while the latter is a common imaging sign in the recovery period of inflammation and is also common in other types of pulmonary infections. In this study, whether the appearance of the fibrosis shadow represents the reversal of the disease or the early manifestation of terminal pulmonary fibrosis needs further follow-up observation [ 20 ]. In addition, with the remission of the disease, the proportions of concomitant signs such as “crazy paving pattern”, “vascular thickening sign”, and “bronchiectasis sign” mentioned above, which represent disease progression, decreased or even disappeared.…”

Section: Discussionmentioning

confidence: 99%

Initial CT features and dynamic evolution of early-stage patients with COVID-19

Wang

Shi

Wei

et al. 2020

Radiology of Infectious Diseases

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Objective To explore the initial CT features and dynamic evolution of early-stage patients with Coronavirus disease 2019 (COVID-19). Methods A total of 126 COVID-19 patients in the early stage were enrolled. The initial CT features and dynamic evolution characteristics of the progression and absorption process from the stage of admission to discharge were retrospectively analyzed in this study. Results The main initial CT features were as follows: bilateral distribution (112/126, 88.9%), diffuse distribution (106/126, 84.1%), multiple lesions (117/126, 92.9%), nodular shapes (84/126, 66.7%), patchy shapes (98/126, 77.8%), pure ground-glass opacities (GGO) (95/126, 75.4%), “vascular thickening sign” (98/126, 77.8%), “air bronchogram sign” (70/126, 55.6%), “crazy paving pattern” (93/126, 73.8%), and “pleura parallel sign” (72/126, 57.1%). The main dynamic evolution characteristics were as follows: ① Imaging findings of the progression process: the main CT changes were increased GGOs with consolidation (118/126, 93.7%), an increased “crazy paving pattern” (104/126, 82.5%), an increased “vascular thickening sign” (105/126, 83.3%), and an increased “air bronchogram sign” (95/126, 75.4%); ② Imaging findings of the absorption process: the main CT changes were the obvious absorption of consolidation displayed as inhomogeneous partial GGOs with fibrosis shadows, the occurrence of a “fishing net on trees sign” (45/126, 35.7%), an increased “fibrosis sign” (40/126, 31.7%), an increased “subpleural line sign” (35/126, 27.8%), a decreased “crazy paving pattern” (19.8%), and a decreased “vascular thickening sign” (23.8%); and ③ In the stage of discharge, the main CT manifestations were further absorption of GGOs, consolidation and fibrosis shadows in the lung, and no appearance of new lesions, with only a small amount of shadow with fibrotic streaks and reticulations remaining in some cases (16/126, 12.7%). Conclusion The initial CT features and dynamic evolution of early-stage patients with COVID-19 have certain characteristics and regularity; CT of the chest is critical for early detection, evaluation of disease severity and follow-up of patients.

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Section: Discussionmentioning

confidence: 99%

Initial CT features and dynamic evolution of early-stage patients with COVID-19

Wang

Shi

Wei

et al. 2020

Radiology of Infectious Diseases

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“…1). Therefore, epidemiological history, clinical manifestations, and the RT-PCR detection of the viral RNA from a respiratory tract sample can be considered to represent the comprehensive analysis necessary to diagnose SARS-CoV-2 infection [24]. Especially, for cases of high clinical suspicion of SARS-CoV-2 infection with a negative RT-PCR result, the combination of repeated swab tests and CT examinations can be helpful for diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics of Coronavirus Disease 2019 in Hangzhou, China: the combination of lopinavir/ritonavir, interferon, and arbidol may be a well choice for antiviral therapy in common cases

Wang

Zhou

et al. 2020

Preprint

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Background Since December 2019, when Coronavirus Disease 2019 (COVID-19) emerged in Wuhan, China, it is currently causing outbreaks in many countries worldwide. No specific therapeutics have yet been proven effective for the treatment of COVID-19. Methods A retrospective, single-center case series study was conducted in a designated hospital for special treatment of COVID-19 in Hangzhou, China. Clinical characteristics of COVID-19 patients were described and compared between the common and severe groups. Multiple linear regression and sensitivity analysis was conducted to evaluate the antiviral effects of the 3-drug combination therapy (lopinavir/ritonavir, interferon, and arbidol). Results One hundred and ten confirmed COVID-19 patients were enrolled, including 99 common cases and 11 severe cases. The mean age was 43.1 years and 54.5% were female. Severe patients might be older (P < 0.01), and have more coexisting disorders (P < 0.01), lower levels of lymphocyte counts (P = 0.016), blood sodium (P = 0.039) and chloride (P < 0.01), and higher levels of C reactive protein and procalcitonin (both P < 0.01). Multiple linear regression and sensitivity analysis indicated that both in Model 1 and Model 2, after adjusted by confounding factors, significant associations between completing the 3-drug combination antiviral therapy (vs. incompleting) and a shorter hospital staying time could be seen (B = -5.970, 95% CI, -9.222, -2.718, P < 0.01, in Model 1; and B = -5.948, 95% CI, -10.622, -1.274, P = 0.014, in Model 2). Conclusions Severe patients might be older and have more comorbidities. The combination of lopinavir/ritonavir, interferon, and arbidol may be a well choice for antiviral therapy, especially in adult common cases.

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“…Studies have shown that CT and X-ray, which are contained in the radiology department, are important imaging modalities for COVID-19, especially in the diagnosis of disease and evaluation of therapeutic effect after treatment [1,5,6]. The Radiology Department of Wuhan Leishenshan Hospital is located in the medical image building and is equipped with three high-performance CT scanners, one of which was special equipment for a medical examination for medical staff or workers, the other two CT were designed as examination machines for patients with COVID-19.…”

Section: Introductionmentioning

confidence: 99%

The role of volunteers in the radiology department of wuhan leishenshan hospital: A mini review from a single study center

Jinxiang¹,

Deng²

2020

Arch Community Med Public Health

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This retrospective report, detailed the volunteer work of the radiology department in Wuhan Leishenshan Hospital at the COVID-19 epidemic period. Under the background of the lack of medical staff, we pointed out that the special hospital is not restricted in one pattern, and, which has laid a solid foundation for the effective development of the medical treatment. During the past two months, the volunteers showed strong humanistic care and selfl ess dedication, which provided manpower guarantee for spreading positive energy and conquering the COVID-19 epidemic as soon as possible. Such a program could serve as a model for common reference throughout the world. The author summarizes the report and pay tribute to the volunteers from all over the world.

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Computed Tomographic Findings in COVID-19

Cited by 3 publications

References 8 publications

Initial CT features and dynamic evolution of early-stage patients with COVID-19

Initial CT features and dynamic evolution of early-stage patients with COVID-19

Clinical characteristics of Coronavirus Disease 2019 in Hangzhou, China: the combination of lopinavir/ritonavir, interferon, and arbidol may be a well choice for antiviral therapy in common cases

The role of volunteers in the radiology department of wuhan leishenshan hospital: A mini review from a single study center

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