Computed tomographic scan of the chest underestimates the number of metastatic lesions in osteosarcoma

Kayton, Mark L.; Huvos, Andrew G.; Casher, Jennifer; Abramson, Sara J.; Rosen, Nancy; Wexler, Leonard H.; Meyers, Paul A.; LaQuaglia, Michael P.

doi:10.1016/j.jpedsurg.2005.10.024

Cited by 146 publications

(104 citation statements)

References 24 publications

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“…The number of thoracotomies was not associated with an increase of postoperative morbidity and mortality rates. We, among others [3,22], believe that open thoracotomy with thorough palpation of the lung remains mandatory even in the light of modern CT scan sensitivity. There is often a discrepancy between the number of radiologically visible metastases and palpable nodules, and many more metastases are identified during surgery than by CT scan [9,15,23].…”

Section: Discussionmentioning

confidence: 99%

Prognostic factors and long-term results of pulmonary metastasectomy for pediatric histologies☆

Tronc

Conter

Marec‐Bérard

et al. 2008

European Journal of Cardio-Thoracic Surgery

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Section: Discussionmentioning

confidence: 99%

Prognostic factors and long-term results of pulmonary metastasectomy for pediatric histologies☆

Tronc

Conter

Marec‐Bérard

et al. 2008

European Journal of Cardio-Thoracic Surgery

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“…It should be noted that there is poor correlation between the presence of overt pulmonary metastasis and lesions seen on imaging. Many lesions which are palpable based on manual exam at the time of thoracotomy are not seen on the preoperative CT and likewise, many nodules noted on CTs have been demonstrated to not be metastatic [47]. Despite this, CT scan remains the gold standard imaging technique for the lungs.…”

Section: Imagingmentioning

confidence: 99%

Osteosarcoma

Moore

Luu

2014

Cancer Treatment and Research

321

251

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“…Some authors report in literature of 142 resections performed on a single lung (9). An open surgical technique is preferred because the whole lung can be explored, in accordance with data supporting the idea that pre-operative CT scan underestimate tumoral deposits found with palpation (15). For osteosarcoma, authors prefer to perform single or staged thoracotomy (9).…”

Section: Indicationsmentioning

confidence: 95%

Metastasectomy in pediatric patients: indications, technical tips and outcomes

Scanagatta

Girelli

2017

J. Thorac. Dis.

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Pulmonary metastasectomy has become a standard procedure for pediatric patients with certain types of solid tumors. Surgeons, expert pediatric oncologists and radiation oncologists contribute with their different skills to the management of pulmonary metastases. Patients are usually scheduled for surgery in case of primary tumor control, in absence of metastases in other organs and when a complete resection is achievable. Nodules are removed through precision resections using electrocautery or laser methods in order to ensure radical surgery with adequate margins. With these techniques, it is possible to preserve the surrounding parenchyma and cause a limited volumetric distortion as compared with staplers. Anatomical resections (segmentectomy, lobectomy or pneumonectomy) should be reserved for selected cases, since major lung resection can only be justified if it leads to a real oncological advantage. Repeated thoracotomies are possible, since there is no theoretical limit to reinterventions. Surgery of lung metastases has a therapeutic and curative role for some histology with acceptable rate of complications but it finds its role only in an aggressive multimodality approach. Indications can be discussed case by case and exceptions can be evaluated also in presence of different evidences. Children affected by metastatic tumors need to be managed by expert multidisciplinary oncological team in referral center with large experience.

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Computed tomographic scan of the chest underestimates the number of metastatic lesions in osteosarcoma

Cited by 146 publications

References 24 publications

Prognostic factors and long-term results of pulmonary metastasectomy for pediatric histologies☆

Prognostic factors and long-term results of pulmonary metastasectomy for pediatric histologies☆

Osteosarcoma

Metastasectomy in pediatric patients: indications, technical tips and outcomes

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