“…Our findings confirm previous findings in the literature, that correlations between severity of symptoms and objective extent of disease (CT or endoscopy) are usually not significant, although may have an impact on treatment outcome [4,8,9]. This means that a rhinosurgeon does not have a general predictive parameter after surgical specimen is analyzed, at least in non-allergic patients with CRS but has to analyze a single symptom and relate it to different parameters of inflammation, considering predisposing factors in an individual patient, in order to predict, to a limited extent, persistence of some bothersome symptoms after sinus surgery.…”