The standard starting point for the percutaneous sacroiliac screw insertion defined by Matta and Saucedo was initially determined for surgeries performed in a prone position. Still, the technique has also been used in surgeries performed in a supine position. Therefore, the cadaveric study aimed to determine the best entry point for the percutaneous insertion of sacroiliac screws depending on the patient's positioning for surgery. K-wires were percutaneously inserted into the sacral body of eight human cadavers. In addition to the standard sacroiliac screw entry point, points located 1 cm and 2 cm cranially from along the line, prolonging the femoral axis, were studied. The K-wires were inserted into the studied entry points on the right side in a supine position and on the left side of the same cadaver in a prone position. The placement of the K-wires was assessed using radiographic imaging and cadaver dissection. The analysis revealed that all three studied entry points enabled the correct placement of orthopedic implants for surgery in the prone position. In turn, for surgery performed in the supine position, the best entry point was located 2 cm cranially from the standard entry point, along the line prolonging the femoral axis.