Computed Tomography Characterization of Renal Cell Tumors in Correlation with Histopathology

Wildberger, Joachim E.; Adam, Gerhard; Boeckmann, W.; Münchau, Andreas; Brauers, A.; Günther, Rolf W.; Füzesi, L.

doi:10.1097/00004424-199710000-00003

Cited by 47 publications

(22 citation statements)

References 23 publications

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“…The results of this study are like other international studies [14][15][16][17][18][19][20][21]. The study conducted by Bird et al [15] and Young et al [16] also proved that RCC and Oncocytoma can be differentiated on the basis of degree on enhancement at multidetector CT.…”

Section: Discussionsupporting

confidence: 87%

“…The study conducted by Bird et al [15] and Young et al [16] also proved that RCC and Oncocytoma can be differentiated on the basis of degree on enhancement at multidetector CT. However, Zhange et al [19] Wildberger et al [20] and Davidson et al [21] were unable to differentiate RCC from Oncocytoma. This was because Young et al and Bird et al has relatively larger cohort of these tumor and used four phase protocol rather than three phase protocol.…”

Section: Discussionmentioning

confidence: 99%

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Role of Computed Tomography in the Pre operative Diagnosis of Clear Cell Renal Carcinoma

Rahman¹,

Jesrani²,

Ali³

2017

J Carcinog Mutagen

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Background: Renal cell carcinoma (RCC) accounts for 3% of all human malignant tumors. The behavior of RCC apparently depends on its subtype. CT scan can provide detailed information about the tumor itself and regarding its precise extension. The pre-histological diagnosis of clear cell renal carcinoma could be made with more precision on the basis of CT scan features and would ultimately play a major role in the prognosis and management of the disease.

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Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Role of Computed Tomography in the Pre operative Diagnosis of Clear Cell Renal Carcinoma

Rahman¹,

Jesrani²,

Ali³

2017

J Carcinog Mutagen

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“…In our institute, most renal parenchymal neoplasms were first suspected by physicians to be RCCs in the process of examinations for non-urological diseases. About 6%-8% of renal tumors were AML, the most common benign lesions [3,5] . The study group contained most of space occupying lesions, both malignant carcinoma and benign tumor, including cysts and renal abscess.…”

Section: Discussionmentioning

confidence: 99%

Computed Tomographic Qualitative Diagnosis of Renal Masses

Xia

2005

Chinese-German J Clin Oncol

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Objective: To analyze the CT findings of renal masses and to investigate the value of CT imaging in qualitative diagnosis of these diseases. Methods: Twenty-eight cases of renal masses, proven surgically and pathologically, were retrospectively analyzed. Pre-and post-contrast CT scans were performed in all cases. Results: Twenty-one of 28 cases (75%) were diagnosed as having malignant tumors with 16 cases of renal cell carcinoma (RCC) showing as irregular-shaped low density soft tissue mass with no or slight enhancement. Ten of 21 cases were diagnosed as having carcinoma of the renal pelvis showing as soft tissue mass in renal pelvis with no or slight enhancement. Three of 21 cases were diagnosed as having nephroblastoma (Wilms' tumor) showing as larger irregular lobucated mass with no enhancement. Three of 28 cases (11%) of benign tumors were diagnosed as having angiomyolipoma (AML). Two cases showed a mixed density mass while another case showed iso-density mass. The soft tissue part of the tumor showed enhancement while the area of fat didn't show any enhancement of the contrast medium. Four of 28 (14%) included 3 cases of renal cysts showing as classic cystic lesions with clear-margin. No enhancement was found. In the remaining one case of renal abscess, CT showed a mixed density mass of soft tissue and cyst with slight enhancement of soft tissue part while no enhancement of cystic part. Conclusion: Pre-contrast and post-contrast CT scans in combination with history play an important role in the diagnosis of renal masses.Computed tomography (CT) is generally accepted as a critical imaging tool for the classification of renal masses. With the development of CT and MRI, there has been an increase in the detection of renal masses. In actual practice, it is still difficult in differentiating benign from malignant renal masses. Differentiation of various renal masses to determine which are benign and require no further study or treatment and which require surgical or other treatment is based on results of both clinical and imaging assessment. This report describes our 1-year experience using spiral CT in 28 patients with renal masses and investigates the value of CT imaging in differential diagnosis of these diseases. Materials and methodsTwenty-eight patients referred for renal masses that had been suspected or detected with spiral CT were enrolled. The study group consisted of 15 men and 13 women aged 2-73 years (mean, 52 years). The main symptoms include lumbar pain, painless hematuria, lower abdominal pain, frequent micturition and abdominal mass. Four cases with no symptom were detected by ultrasound (US) in routine health examinations.Pre-and post-contrast CT scans were performed in all patients (18 cases by GE prospeed CT scanner and 10 cases by Elscint Twin CT scanner). Oral contrast material was administered before scanning in all cases to fill the gastrointestinal tract. Preliminary scan without contrast material was obtained and then contrast material was powerfully injected intravenously at the rate of...

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“…In the published studies, some characteristics such as enhancement pattern, presence or absence of calcification and cystic degeneration, tumor-spreading pattern and vascularity are overlapping among the subtypes of RCC, although a combination of them may help predicting a specific tumor subtype [71][72][73][74][75][76][77][78][79] . The degree of enhancement has been reported to be a unique CT finding for the differentiation of conventional clear cell RCC from nonconventional subtypes [71][72][73] . Jinzaki et al [74] reported that clear cell RCC showed a peak attenuation value in the cortical nephrographic phase of 1 100 HU, whereas for other subtypes the values were !…”

Section: Diagnosis Of Primary Tumormentioning

confidence: 99%

Imaging of Renal Cell Carcinoma: State of the Art and Recent Advances

Sacco¹,

Pinto²,

Totaro³

et al. 2010

Urol Int

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Background and Aim: Renal cell carcinoma (RCC) is the 13th most common cancer worldwide and accounts for 4% of all adult malignancies. Herein the state of the art and recent advances in cross-sectional radiological imaging applied to RCC are reviewed, including ultrasonography, computed tomography, magnetic resonance imaging, and positron emission tomography. Methods: Literature search of peer-reviewed papers published by October 2010. Results: In front of more conventional and widespread imaging tools, such as ultrasonography and computed tomography, an array of newer and attractive radiological modalities are under investigation and show promise to improve our ability to noninvasively detect renal tumors and its recurrences, accurately assess the extent of the disease, and reliably evaluate treatment response, particularly in the era of antiangiogenetic therapy. Conclusions: Recent major advances in radiological imaging techniques have considerably improved our ability to diagnose, stage and follow-up RCC. Further studies are needed to evaluate the potential of most recent and still investigational imaging tools.

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Computed Tomography Characterization of Renal Cell Tumors in Correlation with Histopathology

Cited by 47 publications

References 23 publications

Role of Computed Tomography in the Pre operative Diagnosis of Clear Cell Renal Carcinoma

Role of Computed Tomography in the Pre operative Diagnosis of Clear Cell Renal Carcinoma

Computed Tomographic Qualitative Diagnosis of Renal Masses

Imaging of Renal Cell Carcinoma: State of the Art and Recent Advances

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