Computed Tomography Data Based Rapid Prototyping Model of the Temporal Bone Before Cochlear Implant Surgery

Löppönen, Heikki; Holma, Tuomas; Sorri, Martti; Jyrkinen, Lasse; Karhula, V; Koivula, A.; Ilkko, E.; Laitinen, J; Koivukangas, John; Oikarinen, Jarkko; Alamäki, O

doi:10.3109/00016489709124077

Cited by 27 publications

(8 citation statements)

References 2 publications

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“…One important group of applications concerns the creation of temporal bone models for surgical training and education 18,19,20 . Another group focuses on prosthetic auricular reconstruction 21,22,23 .…”

Section: Discussionmentioning

confidence: 99%

Individually Fitted Hearing Aid Device Manufactured Using Rapid Prototyping Based on Ear CT

et al. 2009

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Rapid prototyping is the technology of automatic freeform fabrication of physical objects from virtual CAD (computer aided design) models. For medical objects the models may be created using data from CT, MR or rotational angiography. We descriobe the case of a 83-year-old woman with essential bilateral hearing impairment as the effect of chronic otitis media. An individually fitted hearing aid was produced for the patient using stereolithography technology and vacuum casting based on data obtained during ear CT. Rapid prototyping may help in manufacturing individually adjusted biomedical prostheses, reducing the time of device production and improving its fitting.

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Section: Discussionmentioning

confidence: 99%

Individually Fitted Hearing Aid Device Manufactured Using Rapid Prototyping Based on Ear CT

et al. 2009

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“…The rapid prototyping models provide a more realistic tool that is easier to handle than computer graphic images. Surgical simulation using models facilitates difficult cranial base surgery and may help reduce surgical complications (Lopponen et al, 1997; Abe, 1998; Begall and Vorwerk, 1998). With the development of a more exact 3D interactive anatomical model for each patient's disease and anatomy, the skull base surgeon not only can achieve a more accurate preoperative assessment leading to a less invasive and less morbid approach, but also can continue to develop and refine new approaches without fear of actual morbidity and mortality.…”

Section: Discussionmentioning

confidence: 99%

Three‐dimensional computational reconstruction of lateral skull base with plastinated slices

et al. 2004

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The goals of this study were to build the 3D reconstructed model of lateral skull base and to explore the spatial relationships of the important structures for providing the morphological basis for lateral skull base surgery and clinical image diagnosis. Blocks with edges of about 80 mm containing the lateral skull base region and adjacent structures were sawn out from both sides of the heads and sectioned on transverse plane at a thickness of 700 m using a plastination technique. On an SGI workstation, a Contours-Marching cubes algorithm was selected to reconstruct the 3D model of the lateral skull base. Accurate alignment of the structures in the serial macroscopic sections was obtained by the employment of the plastination technique. The quality of the reconstructed images was distinct and perfect, specifically, the spatial positions and complicated adjacent relationships of various structures of the lateral skull base can be shown in direct viewing when they are displayed in background of the cranial bony substance. The time spent in displaying or rotating one image including 50 sections was 1.5 sec; all reconstructed structures can be represented individually or jointly and rotated in any plane. The plastination technique and computer-aided 3D reconstruction have an obvious advantage in the study of the complex anatomy of the lateral skull base. Plastination technique provides cross-section images of a higher resolution than those obtained from CT scanning. The computerized 3D reconstruction is important in studying the spatial anatomy of the lateral skull base and can serve as a standard for models created with other techniques. Anat Rec Part A 278A: 437-442, 2004. © 2004 Key words: lateral skull base; 3D reconstruction; plastination; anatomy Surgery of the lateral skull base is often difficult because of the complex anatomy and the delicate structures; some surgeons even considered lesions in this area inoperable or impossible to access adequately (Spetzler et al., 1992;Tedeschi and Rhoton, 1994;Ruckenstein and Denys, 1998). The development of modern lateral skull base surgery has allowed more complete resection of these complex lesions with decreased surgical morbidity, but serious complications (loss of hearing, facial paralysis, or CSF leak) still occasionally occur. To improve the safety of lateral skull base surgery, it is necessary to understand the three-dimensional (3D) anatomy of the temporal bone and the cranial base. Three-dimensional images makes up the disadvantage of 2D images and offer important sug-

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“…Specifically in the biomedical field, 3D stereolithography has been widely adopted in the rapid prototyping and modeling of patient body parts such as the skull, mandible, temporal bone, and aorta (Bakhos et al 2010; Fallahi et al 1999; Kettner et al 2011; Rudman et al 2011; Melchels et al 2010b). Such applications of the stereolithography technique have thus been very useful in the planning and training of craniofacial surgery as well as complex neurosurgery (Paiva et al 2007; Foroutan et al 1998; Lopponen et al 1997; Rudman et al 2011; Melchels et al 2010b). Stereolithography has also been used in the rapid prototyping and fabrication of 3D biocompatible polymers, implantable devices, and biodegradable scaffolds and cell-containing hydrogels for tissue engineering (Cooke et al 2003; Lee et al 2008; Gill and Claevssens 2011; Mapili et al 2005; Shin et al 2011; Chan et al 2010; Melchels et al 2010a; Melchels et al 2010b).…”

Section: Introductionmentioning

confidence: 99%

Micro-ring structures stabilize microdroplets to enable long term spheroid culture in 384 hanging drop array plates

Hsiao

Tung

Kuo

et al. 2011

Biomed Microdevices

116

104

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Using stereolithography, 20 different structural variations comprised of millimeter diameter holes surrounded by trenches, plateaus, or micro-ring structures were prepared and tested for their ability to stably hold arrays of microliter sized droplets within the structures over an extended period of time. The micro-ring structures were the most effective in stabilizing droplets against mechanical and chemical perturbations. After confirming the importance of micro-ring structures using rapid prototyping, we developed an injection molding tool for mass production of polystyrene 3D cell culture plates with an array of 384 such micro-ring surrounded through-hole structures. These newly designed and injection molded polystyrene 384 hanging drop array plates with micro-rings were stable and robust against mechanical perturbations as well as surface fouling-facilitated droplet spreading making them capable of long term cell spheroid culture of up to 22 days within the droplet array. This is a significant improvement over previously reported 384 hanging drop array plates which are susceptible to small mechanical shocks and could not reliably maintain hanging drops for longer than a few days. With enhanced droplet stability, the hanging drop array plates with micro-ring structures provide better platforms and open up new opportunities for high-throughput preparation of microscale 3D cell constructs for drug screening and cell analysis.

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Computed Tomography Data Based Rapid Prototyping Model of the Temporal Bone Before Cochlear Implant Surgery

Cited by 27 publications

References 2 publications

Individually Fitted Hearing Aid Device Manufactured Using Rapid Prototyping Based on Ear CT

Individually Fitted Hearing Aid Device Manufactured Using Rapid Prototyping Based on Ear CT

Three‐dimensional computational reconstruction of lateral skull base with plastinated slices

Micro-ring structures stabilize microdroplets to enable long term spheroid culture in 384 hanging drop array plates

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