Computed tomography diagnosis of eight dogs with brain infarction

Paul, A.; Lenard, Zoe; Mansfield, CS

doi:10.1111/j.1751-0813.2010.00629.x

Cited by 17 publications

(19 citation statements)

References 25 publications

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“…Of these dogs, 2 had no underlying disease identified, while the 3 others had PLN, HAC, or hemangiosarcoma identified (LOE 5, Fair) . In another study of 8 dogs with brain infarction identified via CT, 6 of 8 dogs had concurrent diseases including hypothyroidism, chronic renal disease, pyometra, and HAC (LOE 5, Fair) . A third study of 22 dogs included 4 dogs with concurrent medical diseases that could have predisposed to ischemic stroke.…”

Section: Peco Question: Cerebrovascular Diseasesupporting

confidence: 54%

Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE): Domain 1—Defining populations at risk

deLaforcade

Bacek

Blais

et al. 2019

J Vet Emergen Crit Care

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Objectives:Thrombosis is a well-recognized phenomenon in dogs and cats with a significant impact on morbidity and mortality. Despite growing awareness of thrombosis and increased use of antithrombotic therapy, there is little information in the veterinary literature to guide the use of anticoagulant and antiplatelet medications. The goal of Domain 1 was to explore the association between disease and thrombosis in a number of conditions identified as potential risk factors in the current veterinary literature, to provide the basis for prescribing recommendations.Design: A population exposure comparison outcome format was used to represent patient, exposure, comparison, and outcome. Population Exposure Comparison Outcome questions were distributed to worksheet authors who performed comprehensive searches, summarized the evidence, and created guideline recommendations that were reviewed by domain chairs. Revised guidelines then underwent the Delphi survey process to reach consensus on the final guidelines.Diseases evaluated included immune-mediated hemolytic anemia, protein-losing nephropathy, pancreatitis, glucocorticoid therapy, hyperadrenocorticism, neoplasia, sepsis, cerebrovascular disease, and cardiac disease.Settings: Academic and referral veterinary medical centers.

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Section: Peco Question: Cerebrovascular Diseasesupporting

confidence: 54%

Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE): Domain 1—Defining populations at risk

deLaforcade

Bacek

Blais

et al. 2019

J Vet Emergen Crit Care

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“…Information provided by 3 studies (LOE 5, Fair) suggest that ischemic strokes are more likely the result of a hypercoagulable conditions than a risk factor for thrombosis themselves . None of the dogs included in retrospective studies of PTE, arterial thromboembolism (ATE), portal vein, or splenic vein thrombosis had cerebrovascular disease …”

Section: Guidelinesmentioning

confidence: 99%

American College of Veterinary Emergency and Critical Care (ACVECC) Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE) guidelines: Small animal

Goggs

Blais

Brainard

et al. 2019

J Vet Emergen Crit Care

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Objectives: To systematically review available evidence and establish guidelines related to the risk of developing thrombosis and the management of small animals with antithrombotics. Design: Standardized, systematic evaluation of the literature (identified by searching Medline via PubMed and CAB abstracts) was carried out in 5 domains (Defining populations at risk; Defining rational therapeutic use; Defining evidence-based protocols; Refining and monitoring antithrombotic therapies; and Discontinuing antithrombotic therapies). Evidence evaluation was carried out using Population, Intervention, Comparison, Outcome generated within each domain questions to address specific aims. This was followed by categorization of relevant articles according to level of evidence and quality (Good, Fair, or Poor). Synthesis of these data led to the development of a series of statements. Consensus on the final guidelines was achieved via Delphi-style surveys.Draft recommendations were presented at 2 international veterinary conferences and made available for community assessment, review, and comment prior to final revisions and publication. Settings: Academic and referral veterinary medical centers.Results: Over 500 studies were reviewed in detail. Worksheets from all 5 domains generated 59 statements with 83 guideline recommendations that were refined during 3 rounds of Delphi surveys. A high degree of consensus was reached across all guideline recommendations. Conclusions:Overall, systematic evidence evaluations yielded more than 80 recommendations for the treatment of small animals with or at risk of developing thrombosis. Numerous significant knowledge gaps were highlighted by the evidence reviews undertaken, indicating the need for substantial additional research in this field. K E Y W O R D S ) for their dedicated contributions to this effort. We would also like to thank the members of the veterinary community who attended and contributed to the discussion of the guidelines during the 2018 EVECC Congress and IVECCS sessions and subsequently during the online open-comment stages. CONFLICT OF INTERESTThe authors declare that they have no conflicts of interest.

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“…Three days later, the dog developed acute neurological signs consistent with central dysfunction with right-sided amaurosis, ventromedial strabismus of the left eye, and leftsided Horner's syndrome. 16 Multislice Computed Tomography pre-and postcontrast studies of the brain were performed. A single intraaxial, homogeneous, well-circumscribed, irregularly shaped, hyperattenuating (+/− 62 HU), and noncontrast-enhancing area of 5 mm diameter was observed in the caudal part of the mesencephalon, mildly left-sided, exerting a mild mass effect on the surrounding structures and associated with dilation of the ventricular system ( Figure 1).…”

Section: Case Presentationmentioning

confidence: 99%

CT Scan Features of Presumptive Haemorrhagic Stroke in a Dog with Cushing’s Disease

Liotta

Cavrenne

Peeters

et al. 2014

Case Reports in Veterinary Medicine

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A 9-year-old, intact male, Brie’s shepherd dog, with a 10-day history of depression and tachypnoea developed signs of central neurological dysfunction. 16 Multislice Computed Tomography (CT) pre- and postcontrast studies of the brain revealed a single intra-axial homogeneous well-circumscribed hyperattenuating (+/− 62 HU) and noncontrast-enhancing area, 5 mm in diameter, in the caudal part of the mesencephalon. This finding was highly suggestive of a haemorrhagic event. A pituitary-dependent hyperadrenocorticism (PDH) was identified and is considered likely to be the underlying cause. A repeat CT scan examination, 2 months later, showed almost complete resolution of the brain lesion. The present case describes a solitary 5 mm diameter lesion: the result of intracranial haemorrhage in a dog with presumed PDH.

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Computed tomography diagnosis of eight dogs with brain infarction

Cited by 17 publications

References 25 publications

Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE): Domain 1—Defining populations at risk

Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE): Domain 1—Defining populations at risk

American College of Veterinary Emergency and Critical Care (ACVECC) Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE) guidelines: Small animal

CT Scan Features of Presumptive Haemorrhagic Stroke in a Dog with Cushing’s Disease

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