Coarctation of the aorta is a congenital malformation and typically a disease of childhood and early adulthood, and there is a reduced life expectancy in patients who have not undergone correction. Without correction, the mean life expectancy of patients with coarctation of the aorta is 35 years, and 90% of untreated patients die before reaching the age of 50 years (1). Hypertensive vascular complications, cerebrovascular hemorrhages, aortic valve destruction, premature coronary artery disease, and aortic aneurysms are seen in patients with unrepaired coarctation of the aorta. In addition, dissection or rupture of the aorta is a life-threatening complication of coarctation of the aorta (2). Although the diagnosis of coarctation of the aorta can usually be made on clinical grounds, imaging is necessary to evaluate the exact anatomy of the lesion and to detect associated abnormalities. Recently, multidetector computed tomographic (MDCT) angiography has become a principal imaging modality for the evaluation of thoracic vascular anomalies because of its short acquisition time and high spatial resolution (3). MDCT angiography with multiplanar and three-dimensional techniques is the noninvasive method of choice for assessing the morphology of coarctation of the aorta, particularly to characterize the location, degree, and length of the narrowing; presence of collateral circulation; relationship to the left subclavian artery; and associated cardiovascular abnormalities. It is important to have accurate information about each of these parameters to devise surgical or interventional repair (4, 5).The aim of this study was to evaluate the reliability of 16-slice MDCT angiography for the preoperative morphologic assessment of coarctation of the aorta in adult patients.
Materials and methodsTwenty-four adult patients (17 males and 7 females; median age, 31 years; range, 18-53 years) with clinical suspicion of coarctation of the aorta because of blood pressure gradient in the extremities and weak femoral pulses, who underwent both Doppler echocardiography and MDCT angiography, were included in this study. The symptoms of the patients were dyspnea on exertion (n = 7), chest pain (n = 6), leg weakness on exertion (n = 6), palpitation (n = 2), headache (n = 2), and epistaxis (n = 1). All MDCT images were evaluated for the site, degree and length of the coarctation; the presence of additional cardiac defects, such as patent ductus arteriosus and atrial or ventricular septal defect; and associated vascular anomalies such as an aberrant subclavian artery. The presence of an associated aneurysm and dissection of the thoracic aorta was assessed. The origin, visibility, and course of collateral vessels were also evaluated. Coarctation of the aorta was defined as greater than 25% decrease in vessel diameter. The degree of stenosis was considered severe if the ratio of the coarctation diameter to the distal descending aortic diameter was less MATERIALS AND METHODS Twenty-four adult patients with clinical suspicion of coarctation of the...