Computed Tomography in Acute Cerebral Multiple Sclerosis

Lodder, J.

doi:10.1001/archneur.1983.04050050088015

Cited by 11 publications

(1 citation statement)

References 17 publications

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“…Consistent with the reports published to date, pathological concentrations of contrast medium are often found in acute stages of the MS, even after the administration of the usual quantity of the contrast medium [9,11]. With regard to differential diagnosis, these findings are more difficult to assess.…”

Section: Discussionsupporting

confidence: 57%

Computed tomography in cases of multiple sclerosis: Problems of differential diagnosis in cases with atypical findings

et al. 1988

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The value of computed tomography in the diagnosis of multiple sclerosis is undisputed. The examination is usually carried out as a routine part of the examination program. We report on the CT results of 112 patients with confirmed or suspected MS. Seventy-three patients were examined without, 39 with intravenous administration of a contrast medium. In 41% of the patients, isolated or multiple hypodense foci were found as a manifestation of a multilocular demyelinization process. In 17.8%, only cerebro-atrophic changes were encountered. In 30.3% of the cases the CT showed normal results. In the group of patients examined with a contrast medium, a pathological contrast medium concentration was found in 30.7%. The differential diagnostic demarcation against other diseases of the CNS with similar CT findings and problems of differential diagnosis with MRI are discussed.

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Section: Discussionsupporting

confidence: 57%

Computed tomography in cases of multiple sclerosis: Problems of differential diagnosis in cases with atypical findings

et al. 1988

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Effect of high–dose intravenous steriod administration on contrast‐enhancing computed tomographic scan lesions in multiple sclerosis

Troiano

Hafstein

Ruderman

et al. 1984

Annals of Neurology

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Six consecutive patients with multiple sclerosis and lesions contrast enhancing on computed tomographic scan were treated with high-dose intravenous infusions of methylprednisolone. Double-dose delayed computed tomographic scans were repeated at varying intervals during corticosteroid treatment. Contrast enhancement of sclerotic plaques was reduced or eliminated within as little as 8 hours after the first infusion. Rapid associated partial clinical improvement was noted in four patients with recent exacerbations of disease activity. Similar attenuation of contrast-enhancing plaques and clinical improvement were less predictable following oral corticosteroid therapy in conventional dosage. These studies suggest that the dose, route of administration, and duration of corticosteroid therapy in multiple sclerosis may partially determine the effect of treatment.

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Multiple sclerosis CNS infection

Perkin

1988

Diagnostic Tests in Neurology

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Computed Tomography in Acute Cerebral Multiple Sclerosis

Cited by 11 publications

References 17 publications

Computed tomography in cases of multiple sclerosis: Problems of differential diagnosis in cases with atypical findings

Computed tomography in cases of multiple sclerosis: Problems of differential diagnosis in cases with atypical findings

Effect of high–dose intravenous steriod administration on contrast‐enhancing computed tomographic scan lesions in multiple sclerosis

Multiple sclerosis CNS infection

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