Computed tomography, magnetic resonance imaging, and F-deoxyglucose positron emission computed tomography/computed tomography findings of alveolar soft part sarcoma with calcification in the thigh: A case report

Abstract

BACKGROUND Alveolar soft part sarcoma (ASPS) is an extremely rare malignant sarcoma, accounting for less than 1% of all soft-tissue sarcomas. However, limited information is available on multimodal imaging [computed tomography (CT), magnetic resonance imaging (MRI), and positron emission computed tomography/computed tomography (PET/CT)] of ASPS. CASE SUMMARY This study reports a case of a 35-year-old female patient with ASPS of the left thigh with lung metastasis. The patient presented with a 1-year history of a palpable mass in the lower extremity, which exhibited rapid growth for 3 wk. CT, MRI, and F-deoxyglucose PET/CT examinations were performed. CT showed a slightly hypodense or isodense mass with patchy calcifications. On MRI examination, the mass manifested hyperintensity on T1-weighted, T2-weighted, and diffusion-weighted images with some signal voids. PET/CT images demonstrated an intensely hypermetabolic mass in the left thigh and hypermetabolic nodules in lungs. CONCLUSION ASPS should be considered as a possible diagnosis when a slow-growing mass is detected in the soft tissue of the extremities, with hyperintensity and numerous signal voids on T1-weighted, T2-weighted, and diffusion-weighted images and intense F-deoxyglucose uptake on PET/CT. ASPS can have calcifications on CT.

Alveolar soft part sarcoma of the orbit: A case report

“…To the best of our knowledge, there are no previous reports regarding FDG uptake in a case of orbital ASPS. The maximum FDG uptake of SUV in patients with ASPS in other body parts is 1.8 -10.1 [22][23][24][25] . A previous study reported the presence of thrombosed tumor vessels [3] .…”

Two-Photon CQDs-Based Dual-Mode Nanoprobe for Fluorescence Imaging and Magnetic Resonance Imaging of Intracellular Wide pH

“…Biological imaging is very important in the early identification of an unhealthy state, which has been widely used in biomedical diagnosis. The current biological imaging methods include fluorescence imaging, magnetic resonance imaging (MRI), computed tomography (CT), emission CT, photothermal imaging, Raman imaging, ultrasound imaging, and photoacoustic imaging . Fluorescence imaging has lower cost and higher sensitivity than other imaging tools, and the operation and its use are relatively simple and flexible; therefore, fluorescence biological imaging has been widely used.…”

Angiofibroma of Soft Tissue on MRI and FDG PET/CT Image

“…Our case manifests as a soft tissue mass of the lower limb with intense FDG uptake on PET/CT mimicking malignancy. When soft tissue masses of the lower limbs are encountered, lymphoma, 5 epithelioid hemangioendothelioma, 6 alveolar soft part sarcoma, 7 undifferentiated pleomorphic sarcoma, 8 IgG4-related disease, 9 metastasis, 10,11 intramuscular myxoma, 12 and malignant peripheral nerve sheath tumor 13 should be considered in the differential diagnosis. Except for myxoma (mild FDG uptake), these lesions could have intense FDG uptake.…”