Computed Tomography of Cardiac Valves

Litmanovich, Diana; Kirsch, Jacobo

doi:10.1016/j.rcl.2018.08.011

Cited by 9 publications

(6 citation statements)

References 88 publications

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“…It may be used when echo and CMR assessments are not definitive and to aid preprocedural planning. 26 Assessment of PR severity Determination of the PR severity is less well validated than determination of AR severity.…”

Section: Imaging Evaluation In Pr Pulmonary Valve Morphologymentioning

confidence: 99%

“…69 CCT may also be helpful in assessing MV anatomy but it is major role in is the planning of intervention where it provides accurate assessment of the mitral annulus size, the presence and extent of calcification of the leaflets and subvalvular apparatus, the angle between the anterior MV and LVOT and the presence of coronary artery disease in younger patients. 26…”

Section: Aetiology and Mechanisms Of Mrmentioning

confidence: 99%

“…Finally, CCT could be used for LV and RV volumes and function evaluation or to planimeter ROAs when both echocardiography and CMR are not available or contra-indicated. 26…”

mentioning

confidence: 99%

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Multi-modality imaging assessment of native valvular regurgitation: an EACVI and ESC council of valvular heart disease position paper

Lancellotti

Pîbarot

Chambers

et al. 2022

European Heart Journal - Cardiovascular Imaging

207

107

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Valvular regurgitation represents an important cause of cardiovascular morbidity and mortality. Imaging is pivotal in the evaluation of native valve regurgitation and echocardiography is the primary imaging modality for this purpose. The imaging assessment of valvular regurgitation should integrate quantification of the regurgitation, assessment of the valve anatomy and function, and the consequences of valvular disease on cardiac chambers. In clinical practice, the management of patients with valvular regurgitation largely relies on the results of imaging. It is crucial to provide standards that aim at establishing a baseline list of measurements to be performed when assessing native valve regurgitation. The present document aims to present clinical guidance for the multi-modality imaging assessment of native valvular regurgitation.

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Section: Imaging Evaluation In Pr Pulmonary Valve Morphologymentioning

confidence: 99%

Section: Aetiology and Mechanisms Of Mrmentioning

confidence: 99%

See 1 more Smart Citation

Multi-modality imaging assessment of native valvular regurgitation: an EACVI and ESC council of valvular heart disease position paper

Lancellotti

Pîbarot

Chambers

et al. 2022

European Heart Journal - Cardiovascular Imaging

207

107

View full text Add to dashboard Cite

show abstract

“…CT is not used as a primary diagnostic imaging method for evaluating cardiac valves mainly due to its insufficient temporal and spatial resolutions and high radiation exposure required for data acquisition throughout the entire cardiac cycle. Nevertheless, CT may be used for morphologic and functional assessments of cardiac valves in patients with CHD [ 109 ]. The number of the semilunar valve leaflets may be evaluated on CT.…”

Section: Valvementioning

confidence: 99%

Pediatric Cardiothoracic CT Guideline Provided by the Asian Society of Cardiovascular Imaging Congenital Heart Disease Study Group: Part 2. Contemporary Clinical Applications

et al. 2021

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The use of pediatric cardiothoracic CT for congenital heart disease (CHD) was traditionally limited to the morphologic evaluation of the extracardiac thoracic vessels, lungs, and airways. Currently, the applications of CT have increased, owing to technological advancements in hardware and software as well as several dose-reduction measures. In the previously published part 1 of the guideline by the Asian Society of Cardiovascular Imaging Congenital Heart Disease Study Group, we reviewed the prerequisite technical knowledge for clinical applications in a user-friendly and vendor-specific manner. Herein, we present the second part of our guideline on contemporary clinical applications of pediatric cardiothoracic CT for CHD based on the consensus of experts from the Asian Society of Cardiovascular Imaging CHD Study Group. This guideline describes up-to-date clinical applications effectively in a systematic fashion.

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“…X-ray based ex vivo CT is considered the most powerful technique to provide high spatial resolution of small structures (Liguori et al, 2015;Larsson et al, 2016;Mortensen et al, 2018;Litmanovich et al, 2019). Here we use µ-CT, which is capable of volumetric analysis with a voxel size <20 µm (Holdsworth et al, 2002;Clark et al, 2014;Senter-Zapata et al, 2016) to characterize the 3D morphology of the cardiac compartments and adjacent vessels.…”

Section: Micro-ct Analyses Reveal Outflow Tract Defects In Alk5a Mutantsmentioning

confidence: 99%

Integration of multiple imaging platforms to uncover cardiac defects in adult zebrafish

Bensimon-Brito

Boezio

Cardeira-da-Silva

et al. 2020

Preprint

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Mammalian models have been instrumental to investigate adult heart function and human disease. However, electrophysiological differences with human hearts and high costs emphasize the need for additional models. The zebrafish is a well-established genetic model to study cardiac development and function; however, analysis of cardiac phenotypes in adult specimens is particularly challenging as they are opaque. Here, we optimized and combined multiple imaging techniques including echocardiography, magnetic resonance imaging and micro-computed tomography to identify and analyze cardiac phenotypes in adult zebrafish. Using alk5a/tgfbr1a mutants as a case study, we observed morphological and functional cardiac defects, which were undetected with conventional approaches. Correlation analysis of multiple parameters revealed an association between hemodynamic defects and structural alterations of the heart, as observed clinically. Thus, we report a comprehensive and sensitive platform to identify otherwise indiscernible cardiac phenotypes in adult zebrafish, a model with clear advantages to study cardiac function and disease.

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Computed Tomography of Cardiac Valves

Cited by 9 publications

References 88 publications

Multi-modality imaging assessment of native valvular regurgitation: an EACVI and ESC council of valvular heart disease position paper

Multi-modality imaging assessment of native valvular regurgitation: an EACVI and ESC council of valvular heart disease position paper

Pediatric Cardiothoracic CT Guideline Provided by the Asian Society of Cardiovascular Imaging Congenital Heart Disease Study Group: Part 2. Contemporary Clinical Applications

Integration of multiple imaging platforms to uncover cardiac defects in adult zebrafish

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