Computed Tomography of Splenic Sarcoidosis

Mathieu, Didier; Vanderstigel, Muriel; Schaeffer, A; Vasile, N

doi:10.1097/00004728-198607000-00027

Cited by 16 publications

(3 citation statements)

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“…Clinically, however, less than 20% of patients with sarcoidosis have hepatosplenomegaly and dysfunction of the liver is found in only 4%of patients (1). In most cases liver and spleen involvement was detected casually by multi-imaging (8)(9)(10)(11)(12)), the most frequent described finding is diffuse parenchymal heterogeneity. It is likely that inhomogeneity on abdominal CT is the result of poor imaging resolution of small lesions, which are histologically less than 2 mmin diameter ( 1 3).…”

Section: Discussionmentioning

confidence: 99%

Hepatic and Splenic Sarcoidosis Evaluated by Multiple Imaging Modalities.

et al. 1998

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Wepresent a case of hepatosplenic sarcoidosis. A 51-year-old Japanese male, who was diagnosed to have sarcoidosis 4 years previously, was presented to our hospital because of dry cough and anorexia with weight loss. He had tender hepatosplenomegaly. A dynamic abdominal computed tomography (CT) revealed multiple small low-density areas in both liver and spleen, as well as in magnetic resonance imaging (MRI). The laparoscopic photographs showed many small whitish nodules surfacing on the liver and several tumorous nodules on the spleen. Multiple imaging modalities including dynamic CT and MRI are valuable for detecting focal hepatic and splenic lesions of sarcoidosis. (Internal Medicine 37: 449-453, 1998)

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Section: Discussionmentioning

confidence: 99%

Hepatic and Splenic Sarcoidosis Evaluated by Multiple Imaging Modalities.

et al. 1998

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“…CT can show diffuse hepatosplenomegaly [7,9], but focal hepatic lesions were detected in only 38% and splenic lesion in 33% of patients with biopsy-proved hepatic involvement [7]. Technetium 99 m scan can show normal spleen, nonspecific splenomegaly, heterogeneous uptake, or photon-deficient focal areas [ 14].…”

Section: Discussionmentioning

confidence: 99%

Hepatic and splenic sarcoidosis: Ultrasound and MR imaging

et al. 1993

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Abdominal imaging studies may be performed for various indications in patients known to have sarcoidosis. To assess magnetic resonance imaging (MRI) and sonographic ability to detect abnormalities in sarcoidosis patients with abdominal involvement, a prospective study on 18 selected patients was performed. Besides organomegaly, when present, ultrasound demonstrated normal or increased hepatic parenchymal echogenicity, coarsening of the liver parenchyma with or without discrete nodules, focal calcifications, as well as contour irregularity. Splenic discrete nodules were seen on ultrasound in a single patient. Besides organomegaly, MRI abnormalities include abnormal hepatic signal intensity, discrete nodules, contour irregularity, speculation of small hepatic vascular branches, and a high periportal signal intensity. MRI splenic abnormalities include contour irregularity, nodularity, and abnormal signal intensity. The data presented in this study reveals the spectrum of ultrasound and MRI findings in sarcoidosis patients with abdominal organ involvement, potentially enabling the evaluation of the severity of the disease. MRI appears more sensitive than ultrasound for study of abdominal sarcoidosis.

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“…Sarkoidozda dalak tutulumu genellikle homojendir. Ancak literatürde birkaç olgu sunumu şeklinde, oldukça nadir (%5-15), genellikle düzgün sınırlı ve boyutları 1-15 mm arasında değişen, düşük dansiteli nodüller saptanabilir [13][14][15]. Bizim olgumuzda batın tomografisi ile dalağın homojen olarak tutulduğu gösterilmiştir.…”

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