Computed tomography volume measurements of the liver using a liver segmentation and analysis package: an intra- and inter-rater reliability study

Childs, Jessie; Thoirs, Kerry; Esterman, Adrian

doi:10.5430/jbgc.v5n2p17

Cited by 4 publications

(4 citation statements)

References 29 publications

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“…Further research determined the upper limit of the normal liver volume was 2223 cm 3 using this measurement technique and equation 8 . The three ultrasound measurements used in this equation have demonstrated high intra and inter‐rater reliability 10,11 and near perfect agreement with identical measurements made from CT scans 12 . The equation has demonstrated high intra‐ and inter‐rater reliability 11 .…”

Section: Introductionmentioning

confidence: 83%

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The diagnostic accuracy of using a predictive equation for liver volume derived from simple sonographic measurements in the determination of hepatomegaly

et al. 2021

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Introduction Ultrasound is a safe and inexpensive way to image the adult liver. Recently a valid and reliable equation was developed to determine the size of the adult liver using three simple ultrasound measurements. An upper limit of normal using this equation of 2223 cm3 has been reported. This study aimed to determine the sensitivity, specificity, and predictive values of this cut off to determine hepatomegaly. Methods A low‐risk and a high‐risk group participant group were recruited, each with 30 participants. Each participant had a liver ultrasound and liver volume calculated from the equation and an MRI where liver volume was calculated. The ultrasound volume equation using a hepatomegaly cut off 2223 cm3, was compared to the reference standard of MRI volume using a hepatomegaly cut off of 2185 cm3 as reported by Kromrey et al. Results The ultrasound demonstrated a sensitivity of 90.9% (CI 58.7–99.7), a specificity of 97.9% (CI 89.1–99.9), a positive predictive value of 90.9 (CI 58.7–98.6) and a negative predictive value of 97.9% (CI 88.1–99.7). Conclusion Liver volume calculated by using three linear ultrasound measurements in an equation, and an upper limit of 2223 cm3, has high diagnostic accuracy to determine hepatomegaly.

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Section: Introductionmentioning

confidence: 83%

“…The technician performing the semi‐automated segmentation was blinded to the participant groups. This package has been shown to be reliable when calculating liver volumes 12 …”

Section: Methodsmentioning

confidence: 99%

The diagnostic accuracy of using a predictive equation for liver volume derived from simple sonographic measurements in the determination of hepatomegaly

et al. 2021

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“…Liver volume was calculated using the semi-automated Philips liver segmentation and analysis package (Eindhoven, The Netherlands) which has been shown to be a reliable method. 13 …”

Section: Methodsmentioning

confidence: 99%

What Is the Optimal Time on a Low-Calorie Diet Prior to Laparoscopic Anti-reflux Surgery? A Prospective Case-Controlled Study

Childs

Mudge²,

Esterman

et al. 2022

Journal of Gastrointestinal Surgery

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Introduction A very low-calorie diet (VLCD) or low-calorie diet (LCD) is often used prior to laparoscopic surgery to optimize access to the hiatus. Much debate exists in the literature regarding the required duration for a VLCD or LCD, and how to evaluate the presence of a fatty liver. The aim of our study was to determine the optimal amount of time on an LCD to achieve maximal liver volume reduction, and to assess the accuracy of the InBody 230® vs. bedside ultrasonography vs. magnetic resonance imaging (MRI) in the measurement of liver volume. Methods Seventeen consecutive patients undergoing laparoscopic anti-reflux surgery were recruited into the study. Each patient underwent body composition analysis with the InBody® 230, liver ultrasound, and liver MRI. Patients then began an LCD with a weekly ultrasound assessment until the day before surgery when they underwent repeat body composition analysis, liver ultrasound, and MRI. Results The mean age was 54 years (range 21, 74). Maximal liver volume loss was noted within 3 weeks for 88% of participants, with 47% achieving their maximal liver volume reduction after the first week of an LCD. The mean reduction in liver volume was 16%, 18.6%, and 19% for MRI, ultrasound, and body composition analysis, respectively. Conclusion Close to 90% of patients require 3 weeks or less on an LCD to achieve maximal liver volume loss prior to laparoscopic anti-reflux surgery. Body composition analysis and bedside ultrasonography were both as accurate as the gold standard MRI in the assessment of liver volume.

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“…Computerized Tomography (CT) with contrast is proved to be superior to Magnetic Resonance Imaging (MRI) in liver scanning for the clear demarcation of liver boundaries. The image is then processed in computer-based software for image analysis to obtain volume (Saylisoy et al, 2005;Childs et al, 2015). The automated liver extraction schemes for measuring liver volume showed accurate results when compared with the manual methods (Suzuki et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Application of Stereology in Liver Volume Measurements Using Computed Tomography Scan

et al. 2022

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The application of stereology in hepatobiliary conditions is essential in liver volume estimation. Computerized topographic scan with contrast is a reliable method in liver scanning for precise boundaries demarcation. Liver volumetry varies in relation to different factors. Reports showed a correlation of liver volume with sex and body mass index. Steady relation between age and ethnicity is not established. This study aimed to design a protocol for liver volume measurement and apply it in the estimation of volume among the Sudanese population use stereology. Recruitment of the study population was obtained in the royal scan clinic in Khartoum by making an announcement for participation in the study. Patients with a history of hepatobiliary diseases were excluded. CT abdomen with contrast was obtained in DICOM format and transferred to computer-based software for image analysis. A protocol was designed and validated and then applied in volume estimation using software MRIcro for image display, ImageJ for volume estimation, and Onis 2.6 as image viewer. 300 apparently healthy volunteers were recruited. The protocol reliability result was 0.805. Absolute mean liver volume was 3261.32 ± 1365.313 cm 3 . High liver volume among females was detected than among males. A positive correlation was detected between volume and body mass index (p-value 0.001) regardless of sex. Relation with age showed a rough steady rise till the age of 50 years then it started to decline steadily. The relationship was detected in liver volume with sex and body mass index. More studies are needed to investigate the relationship between ethnicity and age groups.

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Computed tomography volume measurements of the liver using a liver segmentation and analysis package: an intra- and inter-rater reliability study

Cited by 4 publications

References 29 publications

The diagnostic accuracy of using a predictive equation for liver volume derived from simple sonographic measurements in the determination of hepatomegaly

The diagnostic accuracy of using a predictive equation for liver volume derived from simple sonographic measurements in the determination of hepatomegaly

What Is the Optimal Time on a Low-Calorie Diet Prior to Laparoscopic Anti-reflux Surgery? A Prospective Case-Controlled Study

Application of Stereology in Liver Volume Measurements Using Computed Tomography Scan

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