2020
DOI: 10.1007/s00247-019-04593-0
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Computer-aided diagnosis for World Health Organization-defined chest radiograph primary-endpoint pneumonia in children

Abstract: This publication is distributed under the terms of Article 25fa of the Dutch Copyright Act (Auteurswet) with explicit consent by the author. Dutch law entitles the maker of a short scientific work funded either wholly or partially by Dutch public funds to make that work publicly available for no consideration following a reasonable period of time after the work was first published, provided that clear reference is made to the source of the first publication of the work. This publication is distributed under Th… Show more

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Cited by 58 publications
(50 citation statements)
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“…The most important reason is that the chest radiographs of COVID-19 patients must be reviewed by highly trained specialists, which creates large amounts of work for those specialists. Further, it is very difficult to read these images because pneumonia is normally revealed over one or more areas of increased opacity [ 39 ]. This increase may be due to a reduction of the ratio of gas to soft tissue (lung parenchyma, stroma, and blood) in the lungs.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…The most important reason is that the chest radiographs of COVID-19 patients must be reviewed by highly trained specialists, which creates large amounts of work for those specialists. Further, it is very difficult to read these images because pneumonia is normally revealed over one or more areas of increased opacity [ 39 ]. This increase may be due to a reduction of the ratio of gas to soft tissue (lung parenchyma, stroma, and blood) in the lungs.…”
Section: Resultsmentioning
confidence: 99%
“…Texture abnormalities are characterized by diffuse changes [ 45 ]. In these situations, texture analysis may be useful for assigning a probability to each location in the lung fields [ 39 ].…”
Section: Resultsmentioning
confidence: 99%
“…During the training process, the feature extractors near the model input learn primitive image features such as edges, whereas feature extractors deeper into the model learn domain-specific relationships important for the diagnostic task. CNNs have successfully been applied to assist in the detection and classification of human diseases like breast cancer, 7 8 tuberculosis, 9 diabetic retinopathy 10 and pneumonia [11][12][13] directly from images. In some instances, these systems performed as well as trained health professionals.…”
Section: Strengths and Limitations Of This Studymentioning
confidence: 99%
“…A small paediatric dataset of 858 chest X-ray images which was interpreted for PEP by three readers 2 was used to train there model, which achieved a 0.850 auROC. 13 Our study will use 10 000 images interpreted for PEP. Furthermore, by specifying the features that are to be used by a computational prediction method, one may potentially omit features that can be directly learnt from chest X-ray images, which will likely negatively impact model performance.…”
Section: Diagnosing Paediatric Pneumoniamentioning
confidence: 99%
“…While AI for diagnosing respiratory diseases is quickly developing in adults, up to now, its application in children has been limited to the detection of consolidation on chest X-ray images, 6 therefore aiding the diagnosis of pneumonia. 7 However, the opportunities to apply AI technologies in the field of childhood respiratory diseases are quite broad. Apart from supporting the clinician in the detection of radiological findings that are likely to be missed, AI might be useful to screen which tests have to be rapidly evaluated to ensure that children with potentially dangerous imaging findings are seen first, allowing for workflow optimization.…”
mentioning
confidence: 99%