Computer-based quantitative computed tomography image analysis in idiopathic pulmonary fibrosis: A mini review

Usefulness of quantitative computed tomography analysis using a commercially available software program through its simple and automatic procedures in evaluation of emphysema and pulmonary fibrosis

“…In addition to COPD/emphysema, the use of computer-based CT image analysis methods has been previously reported for idiopathic pulmonary fibrosis (IPF), some of which are already utilized in clinical practice at specialist centers [5]. Furthermore, it has been reported that emphysema complicates IPF in approximately 30% of patients [6][7].…”

“…Several software-based CT image analysis methods have been developed for assessing emphysema and interstitial lung disease (ILD), such as the density histogram analysis, the density mask technique, and the texture classification method. Among these, the density mask technique is the most widely used method with a threshold on the order of -950 Hounsfield units (HU), for the quantification of emphysema in patients with COPD [4][5][8][9][10][11]. The density mask technique is also convenient for evaluating the disease status in patients with ILD [12][13].…”

“…The density mask technique is also convenient for evaluating the disease status in patients with ILD [12][13]. The threshold value of -950HU distinguishes emphysema from normal lungs, whereas the threshold value of -700 or -750 HU distinguishes normal lungs from ground-glass opacity [5]. Thus, the density mask technique has universal applicability as a method based on CT values, and exhibits high consistency with visual assessment because the CT values provide clear cut-off points [5].…”

Pulmonary hypertension in combined pulmonary fibrosis and emphysema: A tale of two cities

“…It is reassuring that the findings were also robust using two definitions of CT disease extent. The use of computer‐based CT analysis is being increasingly used in the study of lung disease . A number of techniques have been described, including the texture classification method which allows the differentiation of parenchymal lung disease associated with both ILD and emphysema.…”

“…The use of computer-based CT analysis is being increasingly used in the study of lung disease. [9][10][11][12] A number of techniques have been described, including the texture classification method 9 which allows the differentiation of parenchymal lung disease associated with both ILD and emphysema. The most commonly used texture analysis method is CALIPER.…”