Computer simulations of a new toroidal-cylindrical ion trap mass analyzer

Yu, Quan; Li-Juan, Tang; Ni, Kai; Qian, Xiang; Wang, Xiaohao

doi:10.1002/rcm.7713

Cited by 6 publications

(3 citation statements)

References 33 publications

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“…Ion transfer and analysis were performed between the layers. Yu et al (2016) proposed a novel toroidalcylindrical ion trap mass analyzer, which consists of an outer toroidal ion trap (T-trap) and an inner CIT. The T-trap is mainly used for ion capture and storage during the MS/MS period.…”

Section: Combination Of Ion Trap and Other Analyzers Ion Trap Arraysmentioning

confidence: 99%

Towards Higher Sensitivity of Mass Spectrometry: A Perspective From the Mass Analyzers

Li¹,

Chu²,

Tan³

et al. 2021

Front. Chem.

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Mass spectrometry (MS) is one of the most widely used analytical techniques in many fields. Recent developments in chemical and biological researches have drawn much attention to the measurement of substances with low abundances in samples. Continuous efforts have been made consequently to further improve the sensitivity of MS. Modifications on the mass analyzers of mass spectrometers offer a direct, universal and practical way to obtain higher sensitivity. This review provides a comprehensive overview of the latest developments in mass analyzers for the improvement of mass spectrometers’ sensitivity, including quadrupole, ion trap, time-of-flight (TOF) and Fourier transform ion cyclotron (FT-ICR), as well as different combinations of these mass analyzers. The advantages and limitations of different mass analyzers and their combinations are compared and discussed. This review provides guidance to the selection of suitable mass spectrometers in chemical and biological analytical applications. It is also beneficial to the development of novel mass spectrometers.

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Section: Combination Of Ion Trap and Other Analyzers Ion Trap Arraysmentioning

confidence: 99%

Towards Higher Sensitivity of Mass Spectrometry: A Perspective From the Mass Analyzers

Li¹,

Chu²,

Tan³

et al. 2021

Front. Chem.

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“…For instance, the toroidal ion trap with optimized asymmetric structure has better mass resolution and sensitivity than that with symmetrical geometry. 9,12,13 In fact, using asymmetric structure to create proper components of higher-order field to enhance the mass resolution is effective for different versions of quadrupole devices. [14][15][16][17] Odd-order fields are believed to be the key factors affecting the dipolar resonant excitation.…”

Section: Introductionmentioning

confidence: 99%

“…In recent years, the insistence on constructing symmetric ion traps gradually became loose, because the introduction of some asymmetric components is found to be beneficial to the performance. For instance, the toroidal ion trap with optimized asymmetric structure has better mass resolution and sensitivity than that with symmetrical geometry 9,12,13 . In fact, using asymmetric structure to create proper components of higher‐order field to enhance the mass resolution is effective for different versions of quadrupole devices 14–17 .…”

Section: Introductionmentioning

confidence: 99%

Asymmetric rectilinear ion trap with unidirectional ion ejection capability

et al. 2020

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In this paper, the shapes of the electrodes are modified based on a rectilinear ion trap to achieve unidirectional ejection of ions. The designed asymmetric rectilinear ion trap (ARIT) analyzer adds convex and concave circular structures with a height of 0.5 mm on the two X-electrodes, so that the electric field center of the ion trap is inclined to the concave side. The electric field lines of the convex side are compressed to the concave side. Both simulations and experimental results show that ions are more likely to emit from the slit on the concave side plate when performing ion resonance ejection. The mass spectrum signal intensity can reach more than twice that of the original rectilinear trap when using only one detector. Calculations of the electric field components in the trap show that the even-order higher field proportion in the ion trap has not been significantly affected. Combined with the experimental test results, the study further confirmed that the developed ARIT has no significant loss in mass resolution, tandem mass spectrometry capability, and quantitative analysis capability. The proposed asymmetric structure modification scheme can achieve single-side ejection without significantly affecting other performances of the analyzer, which provides a new idea for the structural optimization of the subsequent ion trap analyzers.

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Geometric optimization of toroidal ion trap based on electric field analysis and SIMION simulation

et al. 2018

International Journal of Mass Spectrometry

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Computer simulations of a new toroidal-cylindrical ion trap mass analyzer

Cited by 6 publications

References 33 publications

Towards Higher Sensitivity of Mass Spectrometry: A Perspective From the Mass Analyzers

Towards Higher Sensitivity of Mass Spectrometry: A Perspective From the Mass Analyzers

Asymmetric rectilinear ion trap with unidirectional ion ejection capability

Geometric optimization of toroidal ion trap based on electric field analysis and SIMION simulation

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