Computer System for Blood Transfusion Service

Cf, Högman; Ramgren, O

doi:10.1111/j.1537-2995.1970.tb00718.x

Cited by 29 publications

(14 citation statements)

References 6 publications

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“…A typical combination can be seen in table II. To assure a constant supply of cells for the machine, a panel of 25 RiR2 and 7 RjRi donors have been selected and reserved: they were registered as regular blood donors and their eligibility to donate is controlled by the computer system currently used in our laboratory [2], The RiBj donors have been used occasionally, in parallel with a K ! iL donor, in situations prompted by desired antigen combina tions.…”

Section: Methodsmentioning

confidence: 99%

Automated Red Cell Antibody Analysis. A Parallel Study

Perrault§¹,

Högman²

1971

Vox Sanguinis

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A parallel study of red cell antibodies was undertaken using two wellknown AutoAnalyzer techniques: the bromelin-methylcellulose (BMC) method as described by Marsh, and the low-ionic strength-Polybrene (LISP) technique of Lalezari. In the present study, minor modifications were made to both methods, without changing the basic principle of antibody detection. The results obtained in this parallel study were compared to standard manual techniques. Screening of 13,135 sera gave 8.7% positive reactions. Of these, 22% were identified manually as being caused by red cell antibodies. Further antibodies could be identified by the machine [described elsewhere]. The sensitivity of the automated methods was generally higher than manual techniques, about 12 times for the BMC and 70 times for the LISP method. Anti-s, -Fy^a, -Jk^a, -Jk^h, and -K were less sensitively detected by the BMC than the most appropriate manual method in a test of 14 commercial typing sera. In no case was the LISP less sensitive than manual techniques. However, hemolyzing antibodies can be missed in rare instances. Anti-D was found at a lower sensitivity level of 20-50 ng/ml with the indirect antiglobulin technique, 5-15 ng/ml with the twostage papain technique, 2-4 ng/ml with the BMC method and 0.2-0.4 ng/ml with the LISP method. Some weak anti-D’s (5%) reacted more strongly in the BMC than LISP. When anti-D preparations used for Rh prophylaxis were quantitated with both methods, the results agreed well.

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Section: Methodsmentioning

confidence: 99%

Automated Red Cell Antibody Analysis. A Parallel Study

Perrault§¹,

Högman²

1971

Vox Sanguinis

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“…Small blood banks commonly use PCs with SCO-Unix (Intel processing unit). The pro grams are developed and maintained by the National Steering Com mittee for EDB in the Blood Transfusion Service, Stockholm and Databyrân for informationsbehandling, Stockholm, Sweden) [13].…”

Section: Computer Systemmentioning

confidence: 99%

Computerized Delivery Control - A Useful and Safe Complement to the Type and Screen Compatibility Testing

Säfwenberg¹,

Högman²,

Cassemar³

1997

Vox Sanguinis

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Objectives: Faster and less labor-intensive crossmatching procedures are needed, but they must be as safe as the traditional antiglobulin method. We present twelve years’ experience with a procedure involving antibody screening, blood group checks, and computerized delivery control (ABCD test). Methods: We use a computer for validation and printing documents and declaring compatibility between patient and blood component, based on screening results and earlierrecorded data about the patient. Results: Of 257,400 units transfused during the period, 90% were declared compatible through the ABCD procedure, and 10% had to be crossmatched. We observed no hemolytic transfusion complications due to a failure of the procedure to detect red cell alloantibodies. Labor in the testing laboratory was reduced by 65% compared to a previous crossmatching period. Fewer blood units were returned unused. Conclusion: The procedure using a computerized system as a guard against human mistakes has been found to be safe and reliable and is now widely used in Sweden.

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“…Which ones? (2) Will it be possible by automation to relieve the staff 1 The system work referred to in this paper has been done by The Committee of Collaborative Electronic Data-Processing Assistance in the Swedish Blood Transfusion Service. In addition to the authors, the committee consists of the following members: Dr.…”

Section: Introductionmentioning

confidence: 99%

“…When considering the use of electronic data processing in blood transfusion ser vices, the following factors should be taken into account: (1) is there a need to make certain procedures in the service safer or more effective? Which ones?…”

Section: Introductionmentioning

confidence: 99%