A noteworthy physical dependence of the hysteresis losses with the axial winding misalignment of superconducting racetrack coils made with commercial Second Generation High Temperature Superconducting (2G-HTS) tapes is reported. A comprehensive study on the influence of the turn-to-turn misalignment factor on the local electromagnetic properties of individual turns, is presented by considering six different coil arrangements and ten amplitudes for the applied alternating transport current, I a , together with an experimentally determined function for the magnetoangular anisotropy properties of the critical current density, J c (B, θ), across the superconducting tape. It has been found that for moderate to low applied currents I a ≤ 0.6 I c0 , with I c0 the self-field critical current of individual tapes, the resulting hysteretic losses under extreme winding deformations can lead to an increase in the energy losses of up to 25% the losses generated by a perfectly wound coil. High level meshing considerations have been applied in order to get a realistic account of the local and global electromagnetic properties of racetrack coils, including a mapping of the flux front dynamics with well defined zones for the occurrence of magnetization currents, transport currents, and flux-free cores, what simultaneously has enabled an adequate resolution for determining the experimental conditions when turn-to-turn misalignments of the order of 20 µm-100 µm in a 20 turns 4 mm wide racetrack coil can lead not only to the increment of the AC losses but also to its reduction.In this sense, we shown that for transport current amplitudes I a > 0.7 I c0 , a slight reduction in the hysteresis losses can be achieved as a consequence of the winding displacement which is at the same time connected with the size reduction of the flux free core at the coil central turns. Our findings can be used as a practical benchmark to determine the relative losses for any 2G-HTS racetrack coil application, unveiling the physical fingerprints that possible coil winding misalignments could infer.