ObjectiveTo evaluate the sequential changes of hemodynamic and metabolic parameters in
patients who underwent aorta no-touch off-pump coronary artery bypass
surgery (OPCAB).MethodsProspective study involving twenty-seven consecutive patients who underwent
aorta no-touch OPCAB. The FloTrac/PreSep/Vigileo™ system (Edwards
Lifesciences) was used to continuously record heart rate (HR), mean arterial
blood pressure (MABP), central venous pressure (CVP), continuous cardiac
index (FCI), stroke volume (SV), stroke volume variation (SVV), and central
venous oxygen saturation (ScvO2). The parameters were assessed 5
min before, during and 5 min after each anastomosis (left anterior
descending [LAD], posterior descending [PD], obtuse marginal [OM] and
diagonal [Dg]). Postoperative lactate was also evaluated.ResultsThere was no significant change in HR and MABP for all anastomoses, except
for MABP during PD grafting (-10.1±2.7 mmHg,
P=0.03). There was a significant decrease in
ScvO2 only during PD and OM anastomoses (-9.4±0.4,
P=0.03; -4.4±0.4, P=0.02;
respectively). CVP drop after PD manipulation was strongly associated with a
higher lactate during the first hours after surgery (r=-0.82;
P=0.001). These hemodynamic changes were transient and
entirely recovered after the heart was returned to its anatomical position.
No significant differences were observed in FCI, SVV, or the systemic
vascular resistance index (SVRI) during all anastomoses, except for a drop
in SVRI during PD grafting (-8.03±2.3, P=0.007). SV
tended to decrease during the procedure in all territories, but with
statistically significant drop only in PD and OM grafting (-10.4±1.2,
P=0.02; -13.6±5.1, P=0.007;
respectively).ConclusionHeart displacement for performing aorta no-touch OPCAB is well tolerated,
with transient and endurable hemodynamic variations.