Concentración de hemoglobina reticulocitaria y ferroterapia en la enfermedad renal crónica: respuesta del grupo de Anemia de la Sociedad Española de Nefrología

Cases, Aleix; Sequera, Patricia de; Quiroga, Borja; Puchades, María Jesús; Martín-Rodríguez, Leyre; Górriz, José Luis; Pórtoles, José

doi:10.1016/j.nefro.2021.06.011

Cited by 1 publication

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“…Main mechanisms have been found that are involved in the pathophysiology of uremic bleeding: Decreased hematocrit, intrinsic alterations in platelet functionalism, toxic effect of plasma factors (uremic toxins), Decreased generation of platelet thromboxane A2, increased synthesis of vascular prostacyclin, quantitative and/or qualitative alterations of the von Wille-brand factor, increased nitric oxide synthesis, hyperparathyroidism, deleterious effect of hemodialysis on platelet function [7].…”

Section: The Visualization Of a Protruding Vessel From A Slight Defec...mentioning

confidence: 99%

Uremic Bleeding in 2 Patients with Dieulafoy&#8217;s Lesion: Case Report and Literature Review

Valdez,

García,

Escamilla

et al. 2024

OJGas

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Dieulafoy's lesions are rare vascular malformations of the gastrointestinal tract. A Dieulafoy's lesion is an aberrant vessel that does not reduce in caliber when it extends from the submucosa to the mucosa. Damage to this artery can cause severe and intermittent arterial bleeding from small vascular stumps that are difficult to visualize. Furthermore, these catastrophic bleeding episodes frequently result in hemodynamic instability and the need for transfusion of multiple blood products. Recently, uremic syndrome has been identified as a risk factor for gastric mucosal lesions. We present two clinical cases of acute digestive bleeding due to Dielafoy lesion with chronic kidney disease as the main cause, where two different therapies were performed endoscopically. We concluded with the results of our patients that the best therapy was the application of the hemostatic hemoclip on the injury vs the injection with adrenaline on the wound site. Uremia is identified as a risk factor for upper gastrointestinal bleeding in patients with pre-existing Dieulafoy's lesion, as well as a higher incidence of new bleeding.

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Section: The Visualization Of a Protruding Vessel From A Slight Defec...mentioning

confidence: 99%

Uremic Bleeding in 2 Patients with Dieulafoy&#8217;s Lesion: Case Report and Literature Review

Valdez,

García,

Escamilla

et al. 2024

OJGas

View full text Add to dashboard Cite

show abstract

Concentración de hemoglobina reticulocitaria y ferroterapia en la enfermedad renal crónica: respuesta del grupo de Anemia de la Sociedad Española de Nefrología

Cited by 1 publication

References 8 publications

Uremic Bleeding in 2 Patients with Dieulafoy&#8217;s Lesion: Case Report and Literature Review

Uremic Bleeding in 2 Patients with Dieulafoy&#8217;s Lesion: Case Report and Literature Review

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Concentración de hemoglobina reticulocitaria y ferroterapia en la enfermedad renal crónica: respuesta del grupo de Anemia de la Sociedad Española de Nefrología

Cited by 1 publication

References 8 publications

Uremic Bleeding in 2 Patients with Dieulafoy&amp;#8217;s Lesion: Case Report and Literature Review

Uremic Bleeding in 2 Patients with Dieulafoy&amp;#8217;s Lesion: Case Report and Literature Review

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Uremic Bleeding in 2 Patients with Dieulafoy’s Lesion: Case Report and Literature Review

Uremic Bleeding in 2 Patients with Dieulafoy’s Lesion: Case Report and Literature Review