Concentrations and chemical species of arsenic in human urine and hair

Yamato, Naohisa

doi:10.1007/bf01697507

Cited by 56 publications

(14 citation statements)

References 17 publications

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“…Surprisingly, the reference subjects showed significantly higher levels of urinary arsenic and antimony (Table 4). However, data of both groups correspond to normal range reference data described by others (17,29,(37)(38)(39)(40)(41)(42)(43)(44) In a separate analysis, the children from the northem Palatinate region did not show higher contents of arsenic or antimony in urine or in scalp hair than the children of south lower Saxony. Thus, a special CM , a = b._ hazard to these children by an increased intake ofcontaminated soil did not seem evident.…”

Section: Methodssupporting

confidence: 84%

Human biomonitoring of arsenic and antimony in case of an elevated geogenic exposure.

Gebel

Suchenwirth

Bolten

et al. 1998

Environ Health Perspect

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Part of the norther Palat e region in Germany is erized by elevated leels of arsenic and antimony in the soil due to the presence ofore sources and former mining activities. In a biomonitoring study, 218 residents were investigted for a putative increased intake of these elements. Seventy-six nonexposd subjects in a rur region in south lower Saxony were chosen as the rrece group. Urine and scalp hair sampes were obtained as su to dein he miteral exposures to arsenic and antimony. The analys were pefr*m ed using graphite furace atomic absorption spectrometry except for arsenic in urine, which was determined by the hydride tecnique. This method does not detect organo ls from sefood, which are not toxicologicaly relevant In the northem Palatinate subjects, sdighy elevated arsenic contents in urine and scalp hair (presumably not hazardous) could be corrldated with an increased arenic content in the soil. On the other hand, the results did not show a correation between the am contents in tie soil ofthe housing area and those in urine and hair. Except for an y in sp hair, age tended to be associatd wi intenal exposure to arsenic and antimony in both study groups. Consumpion of seafood had a slight impact on the levd ofuinary arsenic, which is indi of dte presence oflow quanities of inoranic arsenicas and dimethasinic acid in sefood. Th.e arsenic and antimony contents in scalp hair were positively correated with the 24-hr arsenic io in urine. However, antimony in scalp hair was not correlated with seafood consmptio as was asenic in slp hair and in urine. (19). The purpose of the present study was to investigate the transfer of arsenic and antimony from the environment to humans in the northern Palatinate region. Unlike the studies on arsenic previously described in which the main sources of exposure were arsenic-contaminated drinking water and industrial emissions, this study focuses on soil contaminated with arsenic and antimony as the main source of exposure.Because humans excrete arsenic and antimony mainly via the kidneys (28-30), urinary concentrations were used as valid biomarkers of exposure. Biomonitoring of scalp hair was performed as additional screening to record cumulative exposures. MethodsStudy design and study population. This study was preceded by a project that sought to determine the contents of arsenic and antimony in soil and in plant and animal samples from the northern Palatinate region of Germany. Residents for whom the soil contents of arsenic and antimony in their housing areas were known (one to three soil samples per individual) were asked to participate in the study. To minimize a selection bias, a maximum participation rate was achieved by convincing those residents who did not reply to our first written request to participate. Nonexposed subjects from a rural area in south lower Saxony (Germany) were chosen as the reference group.A six-page questionnaire served to assess factors of interest and confounding variables. All study subjects were interviewed concerning demographic characteristi...

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Section: Methodssupporting

confidence: 84%

Human biomonitoring of arsenic and antimony in case of an elevated geogenic exposure.

Gebel

Suchenwirth

Bolten

et al. 1998

Environ Health Perspect

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“…In humans, inorganic arsenic from ingested water is taken up readily by red blood cells and then distributed primarily to the liver, kidneys, spleen, lungs, intestines, and skin [26][27][28]. The target systems of arsenic exposure comprise the respiratory, gastrointestinal, cardiovascular, nervous, and hematopoietic systems [26].…”

Section: Discussionmentioning

confidence: 99%

Interaction between environmental tobacco smoke and arsenic methylation ability on the risk of bladder cancer

Chen

Guo

et al. 2005

Cancer Causes Control

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“…The comprehensive account of health hazards rendered principally by arsenic (As), cadmium (Cd), lead (Pb), mercury (Hg), Selenium (Se) and Lethium (Li) is represented as follows: ARSENIC Arsenic (As) has many applications: (a) in bronzing, hardening and improving the sphericity of shot, wood preservation, pyrotechnics, varieties of semiconductor devices solar cells, light-emiting diodes, lasers, and integrated circuits); and (b) as pesticides [38]. Arsenic has been reported to vary in: (a) blood, from 1.5 to 2.5 g L-1; (b) hair, from 0.25 to 0.88 g L-1; and (c) urine the average concentrations are between 20 and 50 g L-1 [39,40]. In the environment arsenic is usually found combined with other elements as inorganic and organic forms.…”

Section: The Tolerable Daily Intake Approachmentioning

confidence: 99%

Effect of Toxic Metals on Human Health

Mudgal¹,

Madaan²,

Mudgal³

et al. 2010

TONUTRAJ

139

161

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Metal ions such as iron and copper are among the key nutrients that must be provided by dietary sources. In developing countries, there is an enormous contribution of human activities to the release of toxic chemicals, metals and metalloids into the atmosphere. These toxic metals are accumulated in the dietary articles of man. Numerous foodstuffs have been evaluated for their contributions to the recommended daily allowance both to guide for satisfactory intake and also to prevent over exposure. Further, food chain polluted with toxic metals and metalloids is an important route of human exposure and may cause several dangerous effects on human. In this review we summarized effects of various toxic metals on human health.

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Concentrations and chemical species of arsenic in human urine and hair

Cited by 56 publications

References 17 publications

Human biomonitoring of arsenic and antimony in case of an elevated geogenic exposure.

Human biomonitoring of arsenic and antimony in case of an elevated geogenic exposure.

Interaction between environmental tobacco smoke and arsenic methylation ability on the risk of bladder cancer

Effect of Toxic Metals on Human Health

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