Concentrations of Volatile Fatty Acids and Lactic Acid in the Rumen as Influenced by Diet and Post-Feeding Time

Ghorban, K.; Knox, K. L.; Ward, Gerald M.

doi:10.3168/jds.s0022-0302(66)88128-6

Cited by 17 publications

(2 citation statements)

References 10 publications

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“…Ruminal lactate concentration is greatly dependent on the feed intake and the composition of the diet. When the content of rapidly fermentable carbohydrates in the diet is increased, the ruminal starch catabolism bacteria (like S. bovis ) is also enhanced, resulting in a rapid increase in the concentration of ruminal lactate and ruminal lactate accumulation ( 16 ). While the goats feed on high-roughage diets, the concentration of ruminal lactate is low or even hard to be detected.…”

Section: Discussionmentioning

confidence: 99%

Lactate uptake in the rumen and its contributions to subacute rumen acidosis of goats induced by high-grain diets

Fan²,

Wang³

2022

Front. Vet. Sci.

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Rumen acidosis is the consequence of feeding rapidly fermentable grain diets and it is considered the most common nutritional disorder in intensive feeding ruminants. Due to that mechanism of catabolism and transformation is driven by multi-factors, the role of ruminal lactate and its contribution to subacute rumen acidosis has not been well defined yet. The aim of this study is to evaluate the effects of SARA on the production, absorption, circulation, and transformation of lactate in the rumen. In this study, rumen samples were collected from 12 adult Saanen goats (44.5 ± 4.6 kg BW) equipped with permanent rumen cannula to measure rumen fermentation parameters, organic acids production, microbial profiles, and blood indicators to identify the occurrence of SARA. To further investigate the change in the disappearance rate of ruminal lactate, rumen fluid was collected and a batch culture was performed. The results showed that the clearance rate of ruminal lactate was accelerated by SARA, and the concentration of the ruminal lactate pool was stable. In addition, the rumen liquid dilution rate and the rumen liquid flow rate under the SARA condition of goats were lower than that in normal conditions. The ruminal lactate flow rate had no difference throughout the process of fermentation. However, in vitro data showed that the disappearance of lactate was reduced in SARA. By measuring the conversion of sodium L-[3-13C]-lactate in batch culture, it was found that the percentage of lactate converted to propionate was significantly lower in the SARA treatment and 16.13% more lactate converted to butyrate under SARA condition. However, the percentage of lactate transformed into acetate and butyrate was significantly increased in the SARA treatment than that of control. The relative population of total protozoa count in SARA was significantly reduced, while the relative population of Lactobacillus fermentum, Streptococcus bovis, Butyrivibrio fibrisolvens, Megasphaera elsdenii, and Selenomonas ruminantium in the SARA treatment was significantly induced (p < 0.05). It is concluded that the transformation of lactate into butyrate may promote the development of SARA. These findings provide some references to the diet formulation for preventing SARA.

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Section: Discussionmentioning

confidence: 99%

Lactate uptake in the rumen and its contributions to subacute rumen acidosis of goats induced by high-grain diets

Fan²,

Wang³

2022

Front. Vet. Sci.

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“…Counotte et al (1983) observed a peak La concentration of 0.029 mol/L in the rumen of a dairy cow fed 6 kg of concentrate following a 75-d adaptation. Ghorban et al (1966) demonstrated a range of peak La values depending on carbohydrate source from 0.0022 to 0.0083 mol/L for nonlactating cattle.…”

Section: Model Evaluationmentioning

confidence: 96%

A dynamic mechanistic model of lactic acid metabolism in the rumen

Mills

Crompton

Ellis

et al. 2014

Journal of Dairy Science

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Current feed evaluation systems for ruminants are too imprecise to describe diets in terms of their acidosis risk. The dynamic mechanistic model described herein arises from the integration of a lactic acid (La) metabolism module into an extant model of whole-rumen function. The model was evaluated using published data from cows and sheep fed a range of diets or infused with various doses of La. The model performed well in simulating peak rumen La concentrations (coefficient of determination = 0.96; root mean square prediction error = 16.96% of observed mean), although frequency of sampling for the published data prevented a comprehensive comparison of prediction of time to peak La accumulation. The model showed a tendency for increased La accumulation following feeding of diets rich in nonstructural carbohydrates, although less-soluble starch sources such as corn tended to limit rumen La concentration. Simulated La absorption from the rumen remained low throughout the feeding cycle. The competition between bacteria and protozoa for rumen La suggests a variable contribution of protozoa to total La utilization. However, the model was unable to simulate the effects of defaunation on rumen La metabolism, indicating a need for a more detailed description of protozoal metabolism. The model could form the basis of a feed evaluation system with regard to rumen La metabolism.

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1986

Nitrogen and Energy Nutrition of Ruminants

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Concentrations of Volatile Fatty Acids and Lactic Acid in the Rumen as Influenced by Diet and Post-Feeding Time

Cited by 17 publications

References 10 publications

Lactate uptake in the rumen and its contributions to subacute rumen acidosis of goats induced by high-grain diets

Lactate uptake in the rumen and its contributions to subacute rumen acidosis of goats induced by high-grain diets

A dynamic mechanistic model of lactic acid metabolism in the rumen

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