This paper presents a novel redundantly actuated 2RPU-2SPR parallel manipulator that can be employed to form a five-axis hybrid kinematic machine tool for large heterogeneous complex structural component machining in aerospace field. On the contrary to series manipulators, the parallel manipulator has the potential merits of high stiffness, high speed, excellent dynamic performance, and complicated surface processing capability. First, by resorting to the screw theory, the degree of freedom of the proposed parallel manipulator is briefly addressed with general configuration and verified by Grübler-Kutzbach (G-K) criteria as well. Next, the inverse kinematics solution for such manipulator is deduced in detail; however, the forward kinematics is mathematically intractable. To deal with such problem, the forward kinematics is solved by means of three back propagation (BP) neural network optimization strategies. The remarkable simulation results of the parallel manipulator demonstrate that the BP neural network with position compensation is an appropriate method for solving the forward kinematics because of its various advantages, such as high efficiency and high convergence ratios. Simultaneously, workspaces, including joint space and workspace of the proposed parallel manipulator, are graphically depicted based on the previous research, which illustrate that the proposed manipulator is a good candidate for engineering practical application.