Conceptual design of an RFQ accelerator-based neutron source for boron neutron-capture therapy

Abstract

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Accelerator based epithermal neutron source

“…The project of linear accelerator with electrostatic quadrupoles has been proposed but not implemented at the Berkeley labora tory (US) [41,42]. The proposed accelerator is large in size: it has a diameter of the accelerating tank of 2.4 m, and a length of 6.1 m. A proton quadrupole linacs [43][44][45] and a 2.5 MeV 1 mA tandem accelerator HVEE (High Voltage Engineering Europa) were also proposed but not implemented. For research on BNCT at the University of Birmingham (England), a proton beam with an energy of 2.8 MeV and a current of 1 mA was obtained using Dinamitron [46].…”

Accelerators for cancer therapy

“…Regardless of the target used, moderators must be developed to degrade the neutron spectrum to an average energy ~ 10 keV. Low-energy accelerators currently being developed include tandem cascade accelerators (Shefer et al, 1992), radiofrequency quadrupole linacs (Wangler et al, 1990), Dynamitrons (Allen et al, 1999), and electrostatic quadrupole accelerators (Ludewigt et al, 1997). These accelerators have the advantage a producing neutrons with energies only a few MeV above the optimum energy.…”

Present Status of Boron Neutron Capture Therapy

“…Neutrons can also be produced with conventional accelerators for non-relativistic acceleration of protons ( 85,86). The present development is that of high fluxes of either high energy protons colliding with a heavy metal (87, 88) or low energy protons colliding with lithium (85,86,89).…”

“…The present development is that of high fluxes of either high energy protons colliding with a heavy metal (87, 88) or low energy protons colliding with lithium (85,86,89). In both cases accelerators with extremely high beam currents have to be used ( 0 , 1-1 mA) to induce enough amounts of neutrons.…”