Today’s youth navigate a complex balance between traditional and modern values in a changing world. In this context, education plays a crucial role in transforming society and promoting values that align with the Sustainable Development Goals, such as justice and equality, with Ethics and Christianity supporting these principles. Moreover, Physical Education (PE) is highlighted as a tool for promoting moral development and social inclusion; however, gaps exist in studies focusing on the integration of Ethics and Christian values in PE and sports. The aim of this study was to evaluate the impact of an intervention in the subjects of Ethics and Christianity on social responsibility among university students in PE Sciences. The design of this study was quasi-experimental with quantitative pre- and post-test measures and three groups (one Control Group). The sample comprised 95 students who responded to the University Social Responsibility Scale. Experimental Group 1 participated in Christianity class, and Experimental Group 2 in Ethics class. A Mann–Whitney U, Wilcoxon test, and ANOVA were used. The effect associated with the group variable was confirmed. We have partially affirmed that ethical and religious intervention positively influences students’ perception and practice of social responsibility. Future studies should explore pedagogical models that effectively enhance social responsibility among university students.