The role that technologies have historically played in producing and reproducing global inequalities is well documented. Although technological innovation is associated with progress that does not mean that it necessarily narrows the gap between rich and poor, instead technological inequalities tend to exacerbate other inequalities. This applies also to information and communication technologies (ICT) and Big Data, which play an increasingly important role in humanitarianism. In this article, we address the socio-technical work that is necessary to acquire, process, store and use data and study the power relations that are embedded in these processes. We focus in particular on the use of Big Data in digital humanitarianism and argue that at each stage of the digital data life-cycle (data acquisition, data processing, data storage, and data usage and decision making) different resources are required. These include not only access to hardware, software and connectivity but also the ability to make use of the affordances of digital technologies. We posit that in the context of humanitarianism, ICT and Big Data are a particularly intriguing to study due to their ambivalent position of seeking to address inequalities while at the same time perpetuating them.