Concerning Increase in Antimicrobial Resistance Patterns of Pathogenic Strains of Salmonella Isolated in Poultry Meat Products

Abstract

Salmonella is considered to be one of the major foodborne pathogens associated with the consumption of contaminated poultry meat products. To the best of our knowledge this is the first extended research performed on a number of Salmonella strains isolated during 2011–2021 from poultry meat products in Romania. The aim of this study was to characterize the prevalence of pathogenic Salmonella serovars, antimicrobial susceptibility, and antimicrobial resistance genes in 112 Salmonella isolates recovered from raw poultry meat products. The results showed that Salmonella enterica serovars Enteritidis and Typhimurium were the common serotypes (56%; 25%). Overall, the majority of the isolates were resistant to at least three tested antimicrobials. High resistance was observed for tetracycline (84%), nalidixic acid (78%), and ampicillin (78%) in pathogenic Salmonella isolated during the period 2016–2021. All the pathogenic Salmonella isolated during 2016–2021 tested positive to at least one resistance gene encoding for tetracycline resistance, with the tetA gene being the most prevalent (62%). In addition, 64% (24/37) of the Salmonella isolates carried at least one of the genes (blaCMY-2, blaSHV1, blaTEM1) that code for β-Lactams resistance. The findings in this study showed a high prevalence of multi-drug resistant (MDR) Salmonella serovars in poultry meat products and a concerning increase of resistance patterns. The continuous occurrence of more resistant strains implies that effective measures should be strictly applied in this particular food chain in order to prevent their spread and guarantee microbial safety.

Persistence of Salmonella and Campylobacter in Chicken Meat under the Different Chlorination Techniques in Poultry Processing Plants in Sri Lanka

“…This can be due to the greater usage of tetracycline and quinolone drugs in the poultry industry in Sri Lanka. Similar results were observed in a previous study conducted using Salmonella [54]. Also, the resistant rates and the pattern are in agreement with a previous study in Iran, which revealed that the majority of the Salmonella isolates were resistant to nalidixic acid, tetracycline, and streptomycin [55].…”

Molecular Characterization of Multidrug-Resistant and Extended-Spectrum β-Lactamases-Producing Salmonella enterica Serovars Enteritidis and Typhimurium Isolated from Raw Meat in Retail Markets

“…The findings of the present study revealed notably increased frequencies of ESBL genes, particularly associated with the bla TEM genes, which aligns with previous studies where bla TEM were predominantly detected in Salmonella and Escherichia coli isolated from poultry and food products of animal origin [36,66,67]. The current findings revealed a lower prevalence of bla SHV compared to a previous study which reported a rate of 64% bla SHV in Salmonella serovars in poultry meat products [68].…”

Serovar and sequence type distribution and phenotypic and genotypic antimicrobial resistance of Salmonella originating from pet animals in Chongqing, China

“…Doxycycline, a tetracycline antibiotic, is widely used to treat bacterial diseases in pets. Several different tet (tetracycline resistance) genes have been described as conferring resistance to tetracyclines in bacteria, and studies have shown that Salmonella resistance to tetracycline or doxycycline is frequently due to the presence of tet genes in these bacteria ( 34 – 36 ). Sulfonamides are also widely used to treat bacterial infections in humans and domestic animals but not in pet animals in China ( 37 , 38 ).…”