Concerns of Patients With Ménière Disease in Ethiopia, India, and the United States

Lee, Kevin; Vijayendra, Vinay Kumar; Bedri, Es-hak; Vijayendra, H.; Redleaf, Miriam

doi:10.1001/jamaoto.2019.2663

Cited by 3 publications

(11 citation statements)

References 5 publications

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“…Similar to what Lee et al found in their study, it was recognized that there is a gap in understanding of the patient perspective in head and neck cancer care. Specifically, is the perspective of patients with head and neck cancer different from the physician perspective?…”

supporting

confidence: 82%

“…This small, limited study highlights that the patient perspective differs from the physician perspective. Patient treatment goals may be different from the physician treatment goals.…”

mentioning

confidence: 82%

“…In this issue of JAMA Otolaryngology–Head & Neck Surgery , Lee et al explore how patients with Ménière disease feel about their disease through a survey. The authors note that a previous study found that patients with Ménière disease whose vestibular symptoms were reduced or eliminated did not rate their overall condition as improved.…”

mentioning

confidence: 99%

“…This survey is limited by a low participation rate, lack of generalizability, and lack of psychometric validation of the instruments. It is unclear if the observed differences in the responses are clinically meaningful.…”

mentioning

confidence: 99%

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The Patient Perspective—A Valuable But Untapped Resource in Otolaryngology–Head and Neck Surgery

Chang

2020

JAMA Otolaryngol Head Neck Surg

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Classic Ménière disease is easily identified by the experienced otologist. 1 But how do patients feel about their disease? Surprisingly, patients with Ménière disease whose vestibular symptoms were reduced or eliminated in a recent study did not rate their overall condition as improved. 2 Herein we report a survey of a convenience sample of patients with Ménière disease in Ethiopia, India, and the United States to assess their concerns associated with the disease.

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supporting

confidence: 82%

“…This small, limited study highlights that the patient perspective differs from the physician perspective. Patient treatment goals may be different from the physician treatment goals.…”

mentioning

confidence: 82%

mentioning

confidence: 99%

mentioning

confidence: 99%

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The Patient Perspective—A Valuable But Untapped Resource in Otolaryngology–Head and Neck Surgery

Chang

2020

JAMA Otolaryngol Head Neck Surg

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“…Bilateral SNHL is a major issue for patients with MD, since it has a significant impact on the health-related quality of life (Lopez-Escamez et al 2009; Levo et al 2012). Half of the patients report they are no longer the same person owing to their hearing loss and that they live in fear of another episode (Lee et al 2020). In this study, we have identified clinical predictors to develop SNHL in the contralateral ear, and we have built a predictive model to assess the risk of bilateral SNHL.…”

Section: Discussionmentioning

confidence: 99%

A Predictive Model of Bilateral Sensorineural Hearing Loss in Meniere Disease Using Clinical Data

et al. 2021

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Objectives: Meniere disease (MD) is defined by a clinical syndrome of recurrent attacks of spontaneous vertigo associated with tinnitus, aural fullness, and sensorineural hearing loss (SNHL). Most patients have unilateral SNHL, but some of them will develop contralateral SNHL during the course of the disease. Several studies have reported a frequency of 2 to 73% SNHL in the second ear, according to the duration of disease and the period of follow-up. We hypothesize that unilateral and bilateral MD are different conditions, the first would initially involve the apical turn of the cochlea, while bilateral MD would affect the entire length of the cochlea. The aim of the study is to search for clinical predictors of bilateral SNHL in MD to build a predictive model of bilateral involvement. Design:A retrospective, longitudinal study including two cohorts with a total of 400 patients with definite MD was carried out. The inception cohort consisted of 150 patients with MD and the validation cohort included 250 cases. All of the cases were diagnosed of unilateral MD according to their hearing loss thresholds. The following variables were assessed as predictors of bilateral SNHL for the two cohorts: sex, age of onset, familiar history of MD, migraine and high-frequency hearing loss (HFHL, defined if hearing threshold >20 dB in two or more consecutive frequencies from 2 to 8 KHz). A descriptive analysis was carried out according to the presence of HFHL in the first audiogram for the main variables. By using multiple logistic regression, we built-up several predictive models for the inception cohort and validated it with the replication cohort and merged dataset.Results: Twenty-three (19.3%) and 78 (41%) of patients with HFHL developed contralateral SNHL during the follow-up, in the inception and validation cohorts, respectively. In the inception cohort, the best predictive model included HFHL in the first audiogram (OR = 6.985, p = 0.063) and the absence of migraine (OR = 0.215, p = 0.144) as clinical predictors for bilateral SNHL [area under the curve (AUC) = 0.641, p = 0.002]. The model was validated in the second cohort (AUC = 0.621, p < 0.001). Finally, we merged both datasets to improve the precision of the model including HFHL in the first audiogram (OR = 3.168, p = 0.001), migraine (OR = 0.482, p = 0.036) and age of onset >35 years old (OR = 2.422, p = 0.006) as clinical predictors (AUC = 0.639, p < 0.001).Conclusions: A predictive model including the age of onset, HFHL in the first audiogram and migraine can help to assess the risk of bilateral SNHL in MD. This model may have significant implications for clinical management of patients with MD.

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Increased Risk of Injury in Ménière's Disease and Effects of Treatment: Population‐Based Retrospective Cohort Study

Wu¹,

Lin

Chien

et al. 2022

Otolaryngol.--head neck surg.

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Objective To investigate the risk of injury in patients with Ménière’s disease (MD) and the effects of treatment. Study Design Population-based retrospective cohort study. Setting Data were collected from the Longitudinal Health Insurance Database 2005, containing the information of 2 million randomly selected individuals in Taiwan. Methods We enrolled 90,481 patients with newly diagnosed MD between 2000 and 2017 and 361,924 matched individuals without MD. The study outcomes were diagnoses of all-cause injuries. The Kaplan-Meier method was used to determine the cumulative incidence rates of injury in the MD and non-MD cohorts, and a log-rank test was used to analyze the differences between the cohorts. Cox proportional hazards models were used to calculate the 18-year hazard ratios of each cohort. Results A total of 80,151 patients were diagnosed with injuries during the follow-up period: 24,031 and 56,120 from the MD and non-MD cohorts, respectively. The adjusted hazard ratio (aHR) was 2.19 (95% CI, 2.16-2.35) after adjusting for demographic characteristics and comorbidities. Subgroup analysis revealed that MD was associated with an increased incidence of unintentional and intentional injuries (aHR, 2.24 [95% CI, 2.21-2.41] and 2.05 [95% CI, 2.01-2.19], respectively). Treatment with diuretics, antivertigo medications, or surgery did not reduce the risk of injury (aHR, 0.98 [95% CI, 0.59-1.54], 0.94 [95% CI, 0.58-1.50], and 0.99 [95% CI, 0.61-1.54]). Conclusion MD is independently associated with an increased risk of injuries. Medical or surgical treatment for MD does not reduce the risk of injury in patients with MD. Physicians should counsel patients with MD regarding preventive measures for avoiding subsequent injuries.

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Concerns of Patients With Ménière Disease in Ethiopia, India, and the United States

Cited by 3 publications

References 5 publications

The Patient Perspective—A Valuable But Untapped Resource in Otolaryngology–Head and Neck Surgery

The Patient Perspective—A Valuable But Untapped Resource in Otolaryngology–Head and Neck Surgery

A Predictive Model of Bilateral Sensorineural Hearing Loss in Meniere Disease Using Clinical Data

Increased Risk of Injury in Ménière's Disease and Effects of Treatment: Population‐Based Retrospective Cohort Study

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